sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4ite | TEY | Vitamin D3 receptor |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4ite | TEY | Vitamin D3 receptor | / | 1.000 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.775 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.756 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.749 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.736 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.731 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.716 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.699 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.671 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.665 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.661 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.661 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.660 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.659 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.657 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.655 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.655 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.654 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.653 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.652 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.651 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.650 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.648 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.646 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.646 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.645 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.644 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.644 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.643 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.640 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.640 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.639 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.638 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.638 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.636 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.633 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.632 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.632 | |
| 3m7r | VDX | Vitamin D3 receptor | / | 0.631 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.631 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.628 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.628 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.628 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.628 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.626 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.625 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.623 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.622 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.622 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.620 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.620 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.618 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.617 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.615 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.614 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.612 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.611 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.611 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.610 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.609 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.603 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.602 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.602 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.598 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.596 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.594 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.582 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.574 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.567 | |
| 3w5q | 3KL | Vitamin D3 receptor | / | 0.560 | |
| 4g2i | 0VQ | Vitamin D3 receptor | / | 0.540 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.467 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.465 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.461 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.454 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.449 | |
| 4l8u | 9AZ | Serum albumin | / | 0.449 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.449 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.447 | |
| 1fp2 | HMO | Isoflavone-7-O-methyltransferase 8 | 2.1.1.150 | 0.445 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.444 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 3otq | MZL | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.442 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.440 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.440 |