scPDB - Distribution of Cavity Similarity values of 4eux entry / Site 2

Distribution of Cavity similarities measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4eux	HW1	Nitric oxide synthase, brain	1.14.13.39

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity
4eux	HW1	Nitric oxide synthase, brain	1.14.13.39	1.000
4cx5	HW8	Nitric oxide synthase, brain	1.14.13.39	0.739
3rqm	X2E	Nitric oxide synthase, brain	1.14.13.39	0.722
3png	8CX	Nitric oxide synthase, brain	1.14.13.39	0.696
3ufu	HW8	Nitric oxide synthase, brain	1.14.13.39	0.693
4lux	QJ8	Nitric oxide synthase, brain	1.14.13.39	0.690
3nly	3XC	Nitric oxide synthase, brain	1.14.13.39	0.674
4cx3	HW8	Nitric oxide synthase, brain	1.14.13.39	0.668
3ufq	HW5	Nitric oxide synthase, brain	1.14.13.39	0.655
3tyl	AXW	Nitric oxide synthase, brain	1.14.13.39	0.654
3nlw	3XF	Nitric oxide synthase, brain	1.14.13.39	0.652
3pnf	8BX	Nitric oxide synthase, brain	1.14.13.39	0.640
3rqj	Y2B	Nitric oxide synthase, brain	1.14.13.39	0.632
3rql	X2D	Nitric oxide synthase, brain	1.14.13.39	0.626
3ufv	HW9	Nitric oxide synthase, brain	1.14.13.39	0.626
3nny	59R	Nitric oxide synthase, brain	1.14.13.39	0.622
3nlj	JRR	Nitric oxide synthase, brain	1.14.13.39	0.620
4cx4	HW9	Nitric oxide synthase, brain	1.14.13.39	0.619
3jwt	JI5	Nitric oxide synthase, brain	1.14.13.39	0.618
3rqk	X2C	Nitric oxide synthase, brain	1.14.13.39	0.618
3pne	8AX	Nitric oxide synthase, brain	1.14.13.39	0.617
3nlz	3XD	Nitric oxide synthase, brain	1.14.13.39	0.616
3jx3	JI5	Nitric oxide synthase, brain	1.14.13.39	0.614
3ufo	HW4	Nitric oxide synthase, brain	1.14.13.39	0.613
3ufw	HW0	Nitric oxide synthase, brain	1.14.13.39	0.608
3nln	JRS	Nitric oxide synthase, brain	1.14.13.39	0.606
3n5w	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.605
4imw	1EV	Nitric oxide synthase, brain	1.14.13.39	0.604
3nlq	JRR	Nitric oxide synthase, brain	1.14.13.39	0.601
4imt	1EW	Nitric oxide synthase, brain	1.14.13.39	0.598
4jsf	QJ4	Nitric oxide synthase, brain	1.14.13.39	0.598
3jws	JI4	Nitric oxide synthase, brain	1.14.13.39	0.597
3nlp	JSS	Nitric oxide synthase, brain	1.14.13.39	0.594
3nlv	3XA	Nitric oxide synthase, brain	1.14.13.39	0.591
3uft	HW7	Nitric oxide synthase, brain	1.14.13.39	0.590
3ufr	H5W	Nitric oxide synthase, brain	1.14.13.39	0.585
3svq	JK4	Nitric oxide synthase, brain	1.14.13.39	0.583
4jsi	Q05	Nitric oxide synthase, brain	1.14.13.39	0.580
3svp	JK5	Nitric oxide synthase, brain	1.14.13.39	0.578
4k5g	Q13	Nitric oxide synthase, brain	1.14.13.39	0.577
3ufs	HW6	Nitric oxide synthase, brain	1.14.13.39	0.570
3jx6	JI5	Nitric oxide synthase, brain	1.14.13.39	0.565
3b3p	JI7	Nitric oxide synthase, brain	1.14.13.39	0.564
3n5x	XFK	Nitric oxide synthase, brain	1.14.13.39	0.558
3jx2	JI4	Nitric oxide synthase, brain	1.14.13.39	0.557
3n61	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.557
3n62	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.557
3nnz	59W	Nitric oxide synthase, brain	1.14.13.39	0.555
1rs6	DP2	Nitric oxide synthase, brain	1.14.13.39	0.554
3jx5	J14	Nitric oxide synthase, brain	1.14.13.39	0.553
4lux	H4B	Nitric oxide synthase, brain	1.14.13.39	0.552
4jsg	Q10	Nitric oxide synthase, brain	1.14.13.39	0.547
3n65	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.542
4k5f	Q14	Nitric oxide synthase, brain	1.14.13.39	0.542
3ufp	H4W	Nitric oxide synthase, brain	1.14.13.39	0.541
3n5y	XFL	Nitric oxide synthase, brain	1.14.13.39	0.540
3n5z	XFM	Nitric oxide synthase, brain	1.14.13.39	0.540
3nlr	JRS	Nitric oxide synthase, brain	1.14.13.39	0.540
3rqm	H4B	Nitric oxide synthase, brain	1.14.13.39	0.535
4k5d	1Q6	Nitric oxide synthase, brain	1.14.13.39	0.534
3n5v	XFH	Nitric oxide synthase, brain	1.14.13.39	0.533
3ufq	H4B	Nitric oxide synthase, brain	1.14.13.39	0.533
3png	H4B	Nitric oxide synthase, brain	1.14.13.39	0.532
4imu	1ET	Nitric oxide synthase, brain	1.14.13.39	0.530
4k5e	1Q7	Nitric oxide synthase, brain	1.14.13.39	0.526
2hx4	4HX	Nitric oxide synthase, brain	1.14.13.39	0.524
3nlk	JSS	Nitric oxide synthase, brain	1.14.13.39	0.524
3nlo	JSR	Nitric oxide synthase, brain	1.14.13.39	0.524
1zzq	DP9	Nitric oxide synthase, brain	1.14.13.39	0.520
3jwu	J11	Nitric oxide synthase, brain	1.14.13.39	0.520
3tym	08R	Nitric oxide synthase, brain	1.14.13.39	0.519
1zzu	DP1	Nitric oxide synthase, brain	1.14.13.39	0.516
3nly	H4B	Nitric oxide synthase, brain	1.14.13.39	0.516
3tyl	H4B	Nitric oxide synthase, brain	1.14.13.39	0.515
3jx4	J11	Nitric oxide synthase, brain	1.14.13.39	0.507
3ufu	H4B	Nitric oxide synthase, brain	1.14.13.39	0.506
4cx3	H4B	Nitric oxide synthase, brain	1.14.13.39	0.506
1p6j	DP9	Nitric oxide synthase, brain	1.14.13.39	0.503
3jx0	JI4	Nitric oxide synthase, brain	1.14.13.39	0.500
3b3o	JI3	Nitric oxide synthase, brain	1.14.13.39	0.499
4fvz	H4B	Nitric oxide synthase, brain	1.14.13.39	0.498
1zzr	DP9	Nitric oxide synthase, brain	1.14.13.39	0.493
4cx5	H4B	Nitric oxide synthase, brain	1.14.13.39	0.492
3jx3	H4B	Nitric oxide synthase, brain	1.14.13.39	0.487
3nln	H4B	Nitric oxide synthase, brain	1.14.13.39	0.487
3nlj	H4B	Nitric oxide synthase, brain	1.14.13.39	0.485
3ufv	H4B	Nitric oxide synthase, brain	1.14.13.39	0.485
3jwt	H4B	Nitric oxide synthase, brain	1.14.13.39	0.482
3pnf	H4B	Nitric oxide synthase, brain	1.14.13.39	0.482
2hx4	H4B	Nitric oxide synthase, brain	1.14.13.39	0.477
3nlz	H4B	Nitric oxide synthase, brain	1.14.13.39	0.475
3nny	H4B	Nitric oxide synthase, brain	1.14.13.39	0.474
4eux	H4B	Nitric oxide synthase, brain	1.14.13.39	0.473
3rqj	H4B	Nitric oxide synthase, brain	1.14.13.39	0.472
1k2t	H4B	Nitric oxide synthase, brain	1.14.13.39	0.468
3rqk	H4B	Nitric oxide synthase, brain	1.14.13.39	0.468
3n60	XFN	Nitric oxide synthase, brain	1.14.13.39	0.467
3n66	XFN	Nitric oxide synthase, brain	1.14.13.39	0.466
4jsh	Q15	Nitric oxide synthase, brain	1.14.13.39	0.466
4jsf	H4B	Nitric oxide synthase, brain	1.14.13.39	0.465
1k2u	H4B	Nitric oxide synthase, brain	1.14.13.39	0.463
3n63	XFN	Nitric oxide synthase, brain	1.14.13.39	0.463
4jsj	QJ7	Nitric oxide synthase, brain	1.14.13.39	0.463
4jsi	H4B	Nitric oxide synthase, brain	1.14.13.39	0.461
3nlv	H4B	Nitric oxide synthase, brain	1.14.13.39	0.460
4cx4	H4B	Nitric oxide synthase, brain	1.14.13.39	0.457
4k5g	H4B	Nitric oxide synthase, brain	1.14.13.39	0.457
1p6k	H4B	Nitric oxide synthase, brain	1.14.13.39	0.456
3b3n	H4B	Nitric oxide synthase, brain	1.14.13.39	0.456
3jx5	H4B	Nitric oxide synthase, brain	1.14.13.39	0.456
3nlq	H4B	Nitric oxide synthase, brain	1.14.13.39	0.456
3pne	H4B	Nitric oxide synthase, brain	1.14.13.39	0.454
1m00	H4B	Nitric oxide synthase, brain	1.14.13.39	0.452
3nnz	H4B	Nitric oxide synthase, brain	1.14.13.39	0.452
4imw	H4B	Nitric oxide synthase, brain	1.14.13.39	0.452
3b3p	H4B	Nitric oxide synthase, brain	1.14.13.39	0.450
3e68	AT6	Nitric oxide synthase, inducible	1.14.13.39	0.446
3b3m	H4B	Nitric oxide synthase, brain	1.14.13.39	0.445
4imt	H4B	Nitric oxide synthase, brain	1.14.13.39	0.445