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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4erwSTUCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4erwSTUCyclin-dependent kinase 22.7.11.221.000
2bheBRYCyclin-dependent kinase 22.7.11.220.545
2w05FRTCyclin-dependent kinase 22.7.11.220.545
3rkb12ZCyclin-dependent kinase 22.7.11.220.529
3qxpX64Cyclin-dependent kinase 22.7.11.220.522
2fvdLIACyclin-dependent kinase 22.7.11.220.509
3r9dX6BCyclin-dependent kinase 22.7.11.220.503
1aq1STUCyclin-dependent kinase 22.7.11.220.500
2j9mPY8Cyclin-dependent kinase 22.7.11.220.495
2vu3LZECyclin-dependent kinase 22.7.11.220.494
3lfqA28Cyclin-dependent kinase 22.7.11.220.471
3le62BZCyclin-dependent kinase 22.7.11.220.470
2uznC96Cyclin-dependent kinase 22.7.11.220.467
2r64740Cyclin-dependent kinase 22.7.11.220.464
1gih1PUCyclin-dependent kinase 22.7.11.220.462
3lfnA27Cyclin-dependent kinase 22.7.11.220.446
3r8zZ63Cyclin-dependent kinase 22.7.11.220.442
1v1k3FPCyclin-dependent kinase 22.7.11.220.441
1oiqHDUCyclin-dependent kinase 22.7.11.220.440