sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4edy	9PQ	Hematopoietic prostaglandin D synthase

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4edy	9PQ	Hematopoietic prostaglandin D synthase	/	1.000
3kxo	KXO	Hematopoietic prostaglandin D synthase	/	0.668
4edz	0O5	Hematopoietic prostaglandin D synthase	/	0.632
2vcz	VC3	Hematopoietic prostaglandin D synthase	/	0.624
3vi7	CBD	Hematopoietic prostaglandin D synthase	/	0.603
2vcq	D25	Hematopoietic prostaglandin D synthase	/	0.589
2vd0	D27	Hematopoietic prostaglandin D synthase	/	0.579
2vcx	D26	Hematopoietic prostaglandin D synthase	/	0.548
3vi5	M4M	Hematopoietic prostaglandin D synthase	/	0.544
1d3h	A26	Dihydroorotate dehydrogenase (quinone), mitochondrial	1.3.5.2	0.452
2zs9	ADP	Pantothenate kinase	2.7.1.33	0.448