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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4echFADPolyamine oxidase FMS1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4echFADPolyamine oxidase FMS1/1.000
3cntFADPolyamine oxidase FMS1/0.629
1xpqFADPolyamine oxidase FMS1/0.610
3cn8FADPolyamine oxidase FMS1/0.592
5l3dFADLysine-specific histone demethylase 1A10.543
2iw5FADLysine-specific histone demethylase 1A10.531
4fwjFADLysine-specific histone demethylase 1B10.531
2uxxFAJLysine-specific histone demethylase 1A10.525
4i58FADCyclohexylamine Oxidase/0.512
2yg7FADPutrescine oxidase/0.507
3k7tFAD6-hydroxy-L-nicotine oxidase/0.497
2yg4FADPutrescine oxidase/0.490
3zdnFADMonoamine oxidase N1.4.3.40.489
3rhaFDAPutrescine oxidase/0.482
3kpfFADPolyamine oxidase1.5.3.140.479
3bi2FADPolyamine oxidase FMS1/0.471
1f8rFADL-amino-acid oxidase1.4.3.20.464
3qj4FADRenalase/0.461
4gdpFADPolyamine oxidase FMS1/0.461
1h81FADPolyamine oxidase1.5.3.140.457
5g3tFDAFlavin-dependent L-tryptophan oxidase VioA/0.456
2babFADPutative aminooxidase/0.453
2jb1FADL-amino acid oxidase/0.451
5g3sFDAFlavin-dependent L-tryptophan oxidase VioA/0.451
2ba9FADPutative aminooxidase/0.446
2bacFADPutative aminooxidase/0.441