sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4cnz	ADP	Nitrogen regulatory protein P-II 1

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
4cnz	ADP	Nitrogen regulatory protein P-II 1	/	1.000
2xzw	ATP	Nitrogen regulatory protein P-II	/	0.505
1v3s	ATP	Signaling protein	/	0.496
4co4	ATP	Nitrogen regulatory protein P-II 1	/	0.488
3ncr	ADP	Nitrogen regulatory protein P-II (GlnB-2)	/	0.482
3ta0	ATP	Nitrogen regulatory protein P-II (GlnB-3)	/	0.479
3ncq	ATP	Nitrogen regulatory protein P-II (GlnB-2)	/	0.467
3mhy	ATP	Nitrogen regulatory protein P-II 1	/	0.462
2xtz	GSP	Guanine nucleotide-binding protein alpha-1 subunit	/	0.451
3swq	EPU	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	/	0.451
3ta1	ADP	Nitrogen regulatory protein P-II (GlnB-3)	/	0.450
4kcf	AKM	FAD-dependent oxidoreductase	/	0.448
1x1c	SAH	C-20 methyltransferase	/	0.446
2imk	GTX	AGAP009194-PA	/	0.446