sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4btt | VYR | Coagulation factor X | 3.4.21.6 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4btt | VYR | Coagulation factor X | 3.4.21.6 | 1.000 | |
| 3ens | ENS | Coagulation factor X | 3.4.21.6 | 0.539 | |
| 2xc5 | OYJ | Coagulation factor X | 3.4.21.6 | 0.538 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.486 | |
| 4bti | 7R9 | Coagulation factor X | 3.4.21.6 | 0.483 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.478 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.474 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.468 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.468 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.466 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.465 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.465 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.462 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.461 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.461 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.459 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.459 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.459 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.458 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.456 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.455 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.454 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.453 | |
| 1o5g | CR9 | Prothrombin | 3.4.21.5 | 0.452 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.452 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.452 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.452 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.452 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.451 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.451 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.451 | |
| 2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.450 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.449 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.449 | |
| 4e7r | 0NW | Prothrombin | 3.4.21.5 | 0.449 | |
| 1zrb | 062 | Prothrombin | 3.4.21.5 | 0.448 | |
| 1ghv | 120 | Prothrombin | 3.4.21.5 | 0.447 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.447 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.446 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.446 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.446 | |
| 4ayy | 9MX | Prothrombin | 3.4.21.5 | 0.445 | |
| 4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.444 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.444 | |
| 4lxb | 7R9 | Prothrombin | 3.4.21.5 | 0.444 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.443 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.443 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.443 | |
| 1ypm | RA4 | Prothrombin | 3.4.21.5 | 0.442 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.441 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.441 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.441 | |
| 3ioe | A7D | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 3veu | 0GO | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.440 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.440 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.440 | |
| 2v3h | I25 | Prothrombin | 3.4.21.5 | 0.440 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.440 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.440 |