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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4b1rITCTetracycline repressor protein class D

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4b1rITCTetracycline repressor protein class D/1.000
4b3aTACTetracycline repressor protein class D/0.583
5fklTDCTetracycline repressor protein class D/0.559
5fkmTDCTetracycline repressor protein class D/0.554
1orkATCTetracycline repressor protein class D/0.548
2x9dITCTetracycline repressor protein class D/0.546
2xpvMIYTetracycline repressor protein class D/0.534
4auxXTCTetracycline repressor protein class D/0.532
4v2gITCTetracycline repressor protein class D/0.527
2vkeTACTetracycline repressor protein class D/0.512
2xpuTDCTetracycline repressor protein class D/0.511
2xpwOTCTetracycline repressor protein class D/0.508
4abzT1CTetracycline repressor protein class D/0.508
2o7oDXTTetracycline repressor protein class D/0.498
2fj1CTCTetracycline repressor protein class D/0.493
2trtTACTetracycline repressor protein class D/0.491
2tctCTCTetracycline repressor protein class D/0.469
2x6o2TCTetracycline repressor protein class D/0.465
2xb5I7TTetracycline repressor protein class D/0.449
2xrlDXTTetracycline repressor protein class D/0.448
2gjlFMNNitronate monooxygenase1.13.12.160.441