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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3vc1SAHGeranyl diphosphate 2-C-methyltransferase2.1.1.255

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3vc1SAHGeranyl diphosphate 2-C-methyltransferase2.1.1.2551.000
3vc2SAHGeranyl diphosphate 2-C-methyltransferase2.1.1.2550.601
2yltFADPhenylacetone monooxygenase1.14.13.920.478
4f86SFGGeranyl diphosphate 2-C-methyltransferase2.1.1.2550.475
4krhSAMPhosphoethanolamine N-methyltransferase 2/0.461
2culFADGidA-related protein/0.454
5hhfFDAUDP-galactopyranose mutase/0.453
4d04FADPhenylacetone monooxygenase1.14.13.920.447
2y05NAPProstaglandin reductase 1/0.446
2zb3NDPProstaglandin reductase 21.3.1.480.443
3uj7SAMPhosphoethanolamine N-methyltransferase/0.442
5emhNAPIridoid synthase1.3.1.990.440