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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3t113T1Gag-Pol polyprotein3.4.23.16

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
3t113T1Gag-Pol polyprotein3.4.23.161.000
3nwq2NCGag-Pol polyprotein3.4.23.160.578
3nwxKVSGag-Pol polyprotein3.4.23.160.532
2aquDR7Gag-Pol polyprotein3.4.23.160.527
3nxe2NCProtease/0.527
2p3b3TLV-1 PROTEASE protein/0.525
2p3b3TLV-1 protease/0.525
3ndxRITGag-Pol polyprotein3.4.23.160.524
4ye3G04Gag-Pol polyprotein3.4.23.160.522
1difA85Gag-Pol polyprotein/0.520
3bheBZNGag-Pol polyprotein3.4.23.160.520
1hvjA78Gag-Pol polyprotein/0.518
1hvlA76Gag-Pol polyprotein/0.517
1ec2BEJGag-Pol polyprotein3.4.23.160.514
3cktYDPGag-Pol polyprotein3.4.23.160.514
3el01UNGag-Pol polyprotein3.4.23.160.514
3kf03TLGag-Pol polyprotein/0.514
1k6tXN1Gag-Pol polyprotein3.4.23.160.513
2ieo017Protease/0.508
2nmyROCProtease/0.508
1ec3MS3Gag-Pol polyprotein3.4.23.160.507
1k6cMK1Gag-Pol polyprotein3.4.23.160.507
1ivp1ZKGag-Pol polyprotein/0.506
2qnnQN1Gag-Pol polyprotein3.4.23.160.506
2xyeCXGGag-Pol polyprotein/0.505
4hdfG52Gag-Pol polyprotein3.4.23.160.505
4njvRITProtease/0.503
3ekp478Gag-Pol polyprotein3.4.23.160.502
2qnqQN3Gag-Pol polyprotein3.4.23.160.501
2xyfG40Gag-Pol polyprotein/0.501
3ggxGGXGag-Pol polyprotein/0.501
1k6pXN3Gag-Pol polyprotein3.4.23.160.499
1xl2189Gag-Pol polyprotein3.4.23.160.499
4djoMK5Pol polyprotein/0.499
3aidARQGag-Pol polyprotein3.4.23.160.498
3bxsDRSGag-Pol polyprotein3.4.23.160.498
3ekwDR7Gag-Pol polyprotein3.4.23.160.498
2bqvA1AProtease/0.497
1vijBAYGag-Pol polyprotein/0.496
3ggaGGWGag-Pol polyprotein/0.495
3kfr3TLGag-Pol polyprotein/0.495
3tl9ROCGag-Pol polyprotein3.4.23.160.495
2fxeDR7Gag-Pol polyprotein3.4.23.160.494
2hc0AB2Protease/0.494
3a2oKNJGag-Pol polyprotein3.4.23.160.494
1xl5190Gag-Pol polyprotein3.4.23.160.493
3ndtROCGag-Pol polyprotein3.4.23.160.493
4a4qUX9Pol protein/0.493
1yt9OISGag-Pol polyprotein/0.492
2pk6O33V-1 protease/0.492
3ekqROCGag-Pol polyprotein3.4.23.160.492
3oxxDR7Gag-Pol polyprotein3.4.23.160.492
1hosPHPGag-Pol polyprotein/0.491
1hviA77Protease/0.491
1vikBAYGag-Pol polyprotein/0.491
2aidTHKGag-Pol polyprotein3.4.23.160.491
3kfs3TLGag-Pol polyprotein/0.491
3t3c017Gag-Pol polyprotein3.4.23.160.491
3zptM8YGag-Pol polyprotein3.4.23.160.491
4a6bQG8Gag-Pol polyprotein3.4.23.160.491
1d4yTPVGag-Pol polyprotein3.4.23.160.490
1hvkA79Gag-Pol polyprotein/0.490
2qd8065Gag-Pol polyprotein3.4.23.160.490
2rkfAB1Pol protein/0.490
3linE13Protease/0.490
3qrmNK7Gag-Pol polyprotein3.4.23.160.490
2a4fAAUV-1 protease/0.489
2pwcG3GGag-Pol polyprotein3.4.23.160.489
2qd6065Gag-Pol polyprotein3.4.23.160.489
3qn8NI7Gag-Pol polyprotein3.4.23.160.489
3vf5031Gag-Pol polyprotein3.4.23.160.489
4djqM86Pol polyprotein/0.489
1ebwBEIGag-Pol polyprotein3.4.23.160.488
1k6vXN2Gag-Pol polyprotein3.4.23.160.488
2qhcAB1Protease/0.488
1hshMK1Gag-Pol polyprotein/0.487
2nnkROCProtease/0.487
3em4DR7Gag-Pol polyprotein3.4.23.160.487
3hzc2NCProtease/0.487
2wkz5AHGag-Pol polyprotein/0.486
3el9DR7Gag-Pol polyprotein3.4.23.160.486
3qp0NI8Gag-Pol polyprotein3.4.23.160.486
4j55031Gag-Pol polyprotein3.4.23.160.486
1hxbROCGag-Pol polyprotein3.4.23.160.485
1sh9RITGag-Pol polyprotein3.4.23.160.485
2qi3MZ5Gag-Pol polyprotein/0.485
3d1yROCGag-Pol polyprotein3.4.23.160.485
2fdd385Pol protein/0.484
2pqzG0GGag-Pol polyprotein3.4.23.160.484
2qnpQN2Gag-Pol polyprotein3.4.23.160.484
3em6017Gag-Pol polyprotein3.4.23.160.484
3qbfJHGGag-Pol polyprotein3.4.23.160.484
3s85LK0Gag-Pol polyprotein/0.484
1z1hHBBGag-Pol polyprotein3.4.23.160.483
2cem2AHPol protein/0.483
3dk1G05Gag-Pol polyprotein3.4.23.160.483
3ndwRITGag-Pol polyprotein3.4.23.160.483
3oxcROCProtease/0.483
3sa323XProtease/0.483
3vfa031Gag-Pol polyprotein3.4.23.160.483
2aoe0Q4Gag-Pol polyprotein3.4.23.160.482
3kdcJZPGag-Pol polyprotein3.4.23.160.482
3pwrROCGag-Pol polyprotein3.4.23.160.482
1w5yBE6Gag-Pol polyprotein3.4.23.160.481
3ekt017Gag-Pol polyprotein3.4.23.160.481
3mxeK54Gag-Pol polyprotein3.4.23.160.481
3ttp017Gag-Pol polyprotein3.4.23.160.481
3zpsEQMGag-Pol polyprotein3.4.23.160.481
3bgbLJGGag-Pol polyprotein3.4.23.160.480
3nduROCGag-Pol polyprotein3.4.23.160.480
3nyg2NCGag-Pol polyprotein3.4.23.160.480
1c6zROCProtease/0.479
1fgc2NCGag-Pol polyprotein3.4.23.160.479
1jld0PPGag-Pol polyprotein/0.479
2pyn1UNGag-Pol polyprotein3.4.23.160.479
2r43G3GGag-Pol polyprotein3.4.23.160.479
3vfb031Gag-Pol polyprotein3.4.23.160.479
4hdbG52Gag-Pol polyprotein3.4.23.160.479
4kb9G79Protease/0.479
2p3d3TLProtease/0.478
3jvwDMPGag-Pol polyprotein3.4.23.160.478
2bb9AKCGag-Pol polyprotein3.4.23.160.477
2bpv1INGag-Pol polyprotein3.4.23.160.477
3cyxROCGag-Pol polyprotein3.4.23.160.477
3jw2017Gag-Pol polyprotein3.4.23.160.477
3zpuM8BGag-Pol polyprotein3.4.23.160.477
7upjINUGag-Pol polyprotein3.4.23.160.477
1qbsDMPGag-Pol polyprotein3.4.23.160.476
2bpy3INGag-Pol polyprotein3.4.23.160.476
2r3wG3GGag-Pol polyprotein3.4.23.160.476
1ff02NCGag-Pol polyprotein3.4.23.160.475
1hxwRITGag-Pol polyprotein/0.475
1ida0POGag-Pol polyprotein3.4.23.470.475
2uy0HV1Gag-Pol polyprotein3.4.23.160.475
3ok9G52Gag-Pol polyprotein3.4.23.160.475
1hvsA77Gag-Pol polyprotein/0.474
1t7i017Gag-Pol polyprotein3.4.23.160.474
1wbk568Pol protein/0.474
2i4wKGQProtease/0.474
2nnpROCProtease/0.474
2r3tG4GGag-Pol polyprotein3.4.23.160.474
3o9cK20Pol polyprotein/0.474
3s54017Protease/0.474
3ufnROCGag-Pol polyprotein/0.474
4j5j478Gag-Pol polyprotein3.4.23.160.474
1ohr1UNV-1 PROTEASE protein/0.473
1sbgIM1Gag-Pol polyprotein/0.473
1tcxIM1Gag-Pol polyprotein3.4.23.160.473
2f3kRO1Protease/0.473
2f8g017Gag-Pol polyprotein3.4.23.160.473
2qd7065Gag-Pol polyprotein3.4.23.160.473
3d1xROCGag-Pol polyprotein3.4.23.160.473
3ekyDR7Gag-Pol polyprotein3.4.23.160.473
3kfn3TLGag-Pol polyprotein/0.473
3sa755AProtease/0.473
4hegG52Gag-Pol polyprotein3.4.23.160.473
4rvj478Protease/0.473
1bv7XV6Gag-Pol polyprotein3.4.23.160.472
1d4kPI8Gag-Pol polyprotein3.4.23.160.472
1hpoUNIGag-Pol polyprotein3.4.23.160.472
1k2b0Q4Gag-Pol polyprotein3.4.23.160.472
1rl8RITGag-Pol polyprotein3.4.23.160.472
2qhyMZ1Gag-Pol polyprotein/0.472
3sa5A69Protease/0.472
4djr0KJPol polyprotein/0.472
1a9mU0EGag-Pol polyprotein/0.471
1ec0BEDGag-Pol polyprotein3.4.23.160.471
1fej2NCGag-Pol polyprotein3.4.23.160.471
2pk5075Protease/0.471
3nu9478Gag-Pol polyprotein3.4.23.160.471
3sa4F72Protease/0.471
4k4p3TLGag-Pol polyprotein/0.471
1bai0Q4Gag-Pro polyprotein/0.470
1k1u0Q4Gag-Pol polyprotein3.4.23.160.470
1odw0E8Gag-Pol polyprotein3.4.23.160.470
2hb3GRLProtease/0.470
3djkG55Gag-Pol polyprotein3.4.23.160.470
4a6cQG9Gag-Pol polyprotein3.4.23.160.470
1b6pPI7Gag-Pol polyprotein3.4.23.160.469
1idb0DOGag-Pol polyprotein/0.469
2i4xKGQProtease/0.469
2idw017Protease/0.469
3el4ROCGag-Pol polyprotein3.4.23.160.469
3gi6D78Gag-Pol polyprotein/0.469
4njt017Protease/0.469
1bwaXV6Gag-Pol polyprotein3.4.23.160.468
1t7kBH0Gag-Pol polyprotein3.4.23.160.468
2bpz3INGag-Pol polyprotein3.4.23.160.468
2cen4AHProtease/0.468
2f80017Gag-Pol polyprotein3.4.23.160.468
3sa9A68Protease/0.468
4i8zG08Gag-Pol polyprotein3.4.23.160.468
1ec1BEEGag-Pol polyprotein3.4.23.160.467
1iziQ50Gag-Pol polyprotein3.4.23.160.467
2bpw1INGag-Pol polyprotein3.4.23.160.467
1z1rHBHGag-Pol polyprotein3.4.23.160.466
2a1eIPFGag-Pol polyprotein3.4.23.160.466
2f81017Gag-Pol polyprotein3.4.23.160.466
2qhzMZ2Gag-Pol polyprotein/0.466
2r5q1UNGag-Pol polyprotein/0.466
3el51UNGag-Pol polyprotein/0.466
3lzv017Gag-Pol polyprotein3.4.23.160.466
9hvp0E9Gag-Pol polyprotein/0.466
3kddJZQGag-Pol polyprotein3.4.23.160.465
1izhQ50Protease/0.464
2pym1UNGag-Pol polyprotein3.4.23.160.464
3i2l2NCProtease/0.464
2avm2NCGag-Pol polyprotein3.4.23.160.463
2qi5MZ7Gag-Pol polyprotein/0.463
2qi6MZ8Gag-Pol polyprotein/0.463
3qrsNK8Gag-Pol polyprotein3.4.23.160.463
3s43478Protease/0.463
3uhl2NCGag-Pol polyprotein3.4.23.160.463
1mesDMPGag-Pol polyprotein3.4.23.160.462
1zsr0ZTGag-Pol polyprotein3.4.23.160.462
2fxdDR7Pol polyprotein/0.462
2qci065Gag-Pol polyprotein3.4.23.160.462
3liqE14Protease/0.462
3o9gF53Gag-Pol polyprotein/0.462
3upjU03Gag-Pol polyprotein/0.462
1bdrIM1Gag-Pol polyprotein3.4.23.160.461
1d4lPI9Gag-Pol polyprotein3.4.23.160.461
1zsf0ZSGag-Pol polyprotein3.4.23.160.461
2r38G4GGag-Pol polyprotein3.4.23.160.461
3nu4478Gag-Pol polyprotein3.4.23.160.461
1iiq0ZRGag-Pol polyprotein3.4.23.160.460
1npa3NHGag-Pol polyprotein3.4.23.160.460
1npwLGZGag-Pol polyprotein3.4.23.160.460
2cej1AHPol protein/0.460
2ien017Gag-Pol polyprotein3.4.23.160.460
1ajxAH1Gag-Pol polyprotein3.4.23.160.459
1c6x3INProtease/0.459
1hiv1ZKGag-Pol polyprotein/0.459
1meuDMPGag-Pol polyprotein3.4.23.160.459
3gi4K60Gag-Pol polyprotein/0.459
3k4vROCGag-Pol polyprotein3.4.23.160.459
3o9fK2DGag-Pol polyprotein/0.459
3saa77FProtease/0.459
3sabF78Protease/0.459
4q1y017Gag-Pol polyprotein3.4.23.160.459
1d4sTPVGag-Pol polyprotein3.4.23.160.458
2q54MU1Protease/0.458
2wl05AHGag-Pol polyprotein/0.458
3o9bK2APol polyprotein/0.458
4hdpG52Gag-Pol polyprotein3.4.23.160.458
1ebzBECGag-Pol polyprotein3.4.23.160.457
2b60RITPol polyprotein/0.457
2b7zMK1Gag-Pol polyprotein/0.457
2fde385Gag-Pol polyprotein3.4.23.160.457
3ogqAB1Pol polyprotein/0.457
3st5G89Gag-Pol polyprotein3.4.23.160.457
1bdlIM1Gag-Pol polyprotein3.4.23.160.456
1ebyBEBGag-Pol polyprotein3.4.23.160.456
1fg62NCGag-Pol polyprotein3.4.23.160.456
2hs2017Protease/0.456
2q641UNGag-Pol polyprotein3.4.23.160.456
3dcrKVSProtease/0.456
3s56ROCProtease/0.456
4njsG08Protease/0.456
1hsgMK1Gag-Pol polyprotein/0.455
1sdvMK1Gag-Pol polyprotein3.4.23.160.455
1w5vBE3Gag-Pol polyprotein3.4.23.160.455
4qgiROCGag-Pol polyprotein3.4.23.160.455
6upjNIUGag-Pol polyprotein/0.455
1wbmBLLPol protein/0.454
2qi7MZ9Gag-Pol polyprotein/0.454
3ekv478Gag-Pol polyprotein3.4.23.160.454
3mws017Pol protein/0.454
3nuo478Gag-Pol polyprotein3.4.23.160.454
3qroNK9Gag-Pol polyprotein3.4.23.160.454
1b6mPI6Gag-Pol polyprotein3.4.23.160.453
1daz0Q4Gag-Pol polyprotein3.4.23.160.453
1g2kNM1Gag-Pol polyprotein3.4.23.160.453
1qbu846Gag-Pol polyprotein3.4.23.160.453
2upjU02Gag-Pol polyprotein3.4.23.160.453
2z54AB1Gag-Pol polyprotein3.4.23.160.453
3el1DR7Gag-Pol polyprotein3.4.23.160.453
3o9iA61Gag-Pol polyprotein/0.453
1dw60Q4Gag-Pol polyprotein3.4.23.160.452
1ffi2NCGag-Pol polyprotein3.4.23.160.452
2avvMK1Gag-Pol polyprotein3.4.23.160.452
2q3kMUWGag-Pol polyprotein/0.452
3ggu017Gag-Pol polyprotein3.4.23.160.452
1d4iBEGGag-Pol polyprotein3.4.23.160.451
1hvhQ82Gag-Pol polyprotein3.4.23.160.451
1n49RITGag-Pol polyprotein3.4.23.160.451
1w5xBE5Gag-Pol polyprotein3.4.23.160.451
3tog079Gag-Pol polyprotein2.7.7.490.451
4dfg0JVGag-Pol polyprotein3.4.23.160.451
4djpM73Pol polyprotein/0.451
1b6kPI5Gag-Pol polyprotein3.4.23.160.450
1g35AHFGag-Pol polyprotein3.4.23.160.450
1sguMK1Gag-Pol polyprotein3.4.23.160.450
2i4uDJRProtease/0.450
2qi1MZ4Gag-Pol polyprotein/0.450
4dqc017Gag-Pol polyprotein/0.450
4dqh017Gag-Pol polyprotein/0.450
1a940Q4Gag-Pol polyprotein3.4.23.160.449
1a8g2Z4Gag-Pol polyprotein3.4.23.160.448
1hvrXK2Gag-Pol polyprotein/0.448
1npvL27Gag-Pol polyprotein3.4.23.160.448
1sdtMK1Gag-Pol polyprotein3.4.23.160.448
2avsMK1Gag-Pol polyprotein3.4.23.160.448
2fleAIProtease/0.448
2i4vDJRV-1 protease/0.448
3o9aK14Pol polyprotein/0.448
1metDMPGag-Pol polyprotein3.4.23.160.447
2p3a3TLPol protein/0.447
2qak1UNGag-Pol polyprotein3.4.23.160.447
3bgcLJHGag-Pol polyprotein3.4.23.160.447
3ekx1UNGag-Pol polyprotein3.4.23.160.447
3jvy017Gag-Pol polyprotein3.4.23.160.447
3nu5478Gag-Pol polyprotein3.4.23.160.447
3vf7031Gag-Pol polyprotein3.4.23.160.447
3wsjMK1Protease/0.447
1hiiC20Gag-Pol polyprotein/0.446
3bva2NCGag-Pol polyprotein3.4.23.160.446
3i6oGR6Gag-Pol polyprotein3.4.23.160.446
3sacAF8Protease/0.446
4dqe017Gag-Pol polyprotein/0.446
1c70L75Protease/0.445
1fg80Q4Gag-Pol polyprotein3.4.23.160.445
1hwr216Gag-Pol polyprotein3.4.23.160.445
1qbrXV6Gag-Pol polyprotein3.4.23.160.445
2q5kAB1Protease/0.445
3livE16Protease/0.445
3oxw017Gag-Pol polyprotein3.4.23.160.445
3qaaG04Gag-Pol polyprotein3.4.23.160.445
1hihC20Gag-Pol polyprotein/0.444
1mtrPI6Gag-Pol polyprotein3.4.23.160.444
2qi0MZ3Gag-Pol polyprotein/0.444
3ec0GRLGag-Pol polyprotein3.4.23.470.444
3nls016Gag-Pol polyprotein3.4.23.160.444
5upjUINGag-Pol polyprotein/0.444
1fff0Q4Gag-Pol polyprotein3.4.23.160.443
1odyLP1Gag-Pol polyprotein3.4.23.160.443
2p3c3TLProtease/0.443
2q631UNGag-Pol polyprotein3.4.23.160.443
1kzkJE2Gag-Pol polyprotein3.4.23.160.442
1muiAB1Protease/0.442
3d1z017Gag-Pol polyprotein3.4.23.160.442
3gi5K62Gag-Pol polyprotein/0.442
3litE15Protease/0.442
3oxv478Gag-Pol polyprotein3.4.23.160.442
3qpjN4IGag-Pol polyprotein3.4.23.160.442
3sa8K83Protease/0.442
2uxzHI1Gag-Pol polyprotein3.4.23.160.441
3fx5KNIGag-Pol polyprotein3.4.23.160.441
1c6yMK1Protease/0.440
1sduMK1Gag-Pol polyprotein3.4.23.160.440
3em3478Gag-Pol polyprotein3.4.23.160.440
3lzs017Gag-Pol polyprotein3.4.23.160.440
3oy4017Gag-Pol polyprotein3.4.23.160.440