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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3s79ASDAromatase1.14.14.14

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3s79ASDAromatase1.14.14.141.000
4dvq1CACytochrome P450 11B2, mitochondrial1.14.15.40.485
4k9u5AWCytochrome P450 3A4/0.469
3ibdCPZCytochrome P450 2B61.14.130.467
4k9v6AWCytochrome P450 3A4/0.464
4ejh0QACytochrome P450 2A131.14.14.10.459
3tk3CPZCytochrome P450 2B41.14.14.10.453
1suoCPZCytochrome P450 2B41.14.14.10.452
3t3r9PLCytochrome P450 2A61.14.130.452
3t3q9PLCytochrome P450 2A61.14.130.451
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.449
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.449
4uymVOR14-alpha sterol demethylase Cyp51B/0.446
2q9fC3SCholesterol 24-hydroxylase/0.444
3ua108YCytochrome P450 3A4/0.442