Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3s3gTLTAldose reductase1.1.1.21

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3s3gTLTAldose reductase1.1.1.211.000
1pwmFIDAldose reductase1.1.1.210.630
1ef3FIDAldose reductase1.1.1.210.624
2iqdLPAAldose reductase1.1.1.210.587
3u2cSUZAldose reductase1.1.1.210.553
2inzOHPAldose reductase1.1.1.210.535
4gabFIDAldo-keto reductase family 1 member B101.1.10.504
2pdmZSTAldose reductase1.1.1.210.503
3v35NTIAldose reductase1.1.1.210.502
2hvnZSTAldose reductase1.1.1.210.499
2pd9FIDAldose reductase1.1.1.210.499
2f2kTGGAldose reductase1.1.1.210.490
2is72CLAldose reductase1.1.1.210.486
2pdyFIDAldose reductase1.1.1.210.485
2pdwFIDAldose reductase1.1.1.210.480
3p2vDOYAldose reductase1.1.1.210.475
2nvcITAAldose reductase1.1.1.210.471
2pdkSBIAldose reductase1.1.1.210.467
2pdiZSTAldose reductase1.1.1.210.466
2pdg47DAldose reductase1.1.1.210.465
1az1ALRAldose reductase1.1.1.210.463
1ah0SBIAldose reductase1.1.1.210.447
2pdj393Aldose reductase1.1.1.210.442