sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3qwc | 98P | Prothrombin | 3.4.21.5 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 1.000 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.718 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.695 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.690 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.688 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.686 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.686 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.683 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.674 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.672 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.670 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.668 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.665 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.661 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.660 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.658 | |
| 2cf8 | ESH | Prothrombin | 3.4.21.5 | 0.656 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.653 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.650 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.650 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.648 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.647 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.643 | |
| 1ypm | RA4 | Prothrombin | 3.4.21.5 | 0.638 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.638 | |
| 2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.637 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.637 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.634 | |
| 1bcu | PRL | Prothrombin | 3.4.21.5 | 0.631 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.631 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.628 | |
| 1ypj | UIB | Prothrombin | 3.4.21.5 | 0.625 | |
| 1o5g | CR9 | Prothrombin | 3.4.21.5 | 0.624 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.624 | |
| 4ayy | 9MX | Prothrombin | 3.4.21.5 | 0.623 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.621 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.619 | |
| 2cf9 | 348 | Prothrombin | 3.4.21.5 | 0.618 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.615 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.614 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.613 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.608 | |
| 1ghv | 120 | Prothrombin | 3.4.21.5 | 0.605 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.601 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.597 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.597 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.595 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.591 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.587 | |
| 4lxb | 7R9 | Prothrombin | 3.4.21.5 | 0.586 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.584 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.583 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.582 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.582 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.580 | |
| 2v3h | I25 | Prothrombin | 3.4.21.5 | 0.580 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.576 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.575 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.575 | |
| 1ypk | CCR | Prothrombin | 3.4.21.5 | 0.573 | |
| 2zg0 | 50U | Prothrombin | 3.4.21.5 | 0.567 | |
| 1a4w | QWE | Prothrombin | 3.4.21.5 | 0.563 | |
| 4ayv | 9MQ | Prothrombin | 3.4.21.5 | 0.563 | |
| 1zrb | 062 | Prothrombin | 3.4.21.5 | 0.561 | |
| 1k22 | MEL | Prothrombin | 3.4.21.5 | 0.560 | |
| 2zfp | 19U | Prothrombin | 3.4.21.5 | 0.555 | |
| 3qto | 10P | Prothrombin | 3.4.21.5 | 0.552 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.549 | |
| 1mu8 | CDB | Prothrombin | 3.4.21.5 | 0.546 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.545 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.544 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.543 | |
| 1riw | OSC | Prothrombin | 3.4.21.5 | 0.542 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.541 | |
| 1k21 | IGN | Prothrombin | 3.4.21.5 | 0.540 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.539 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.538 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.538 | |
| 4e7r | 0NW | Prothrombin | 3.4.21.5 | 0.538 | |
| 3qtv | 06P | Prothrombin | 3.4.21.5 | 0.537 | |
| 3utu | 1TS | Prothrombin | 3.4.21.5 | 0.537 | |
| 1c4v | IH2 | Prothrombin | 3.4.21.5 | 0.531 | |
| 1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.529 | |
| 4bah | MEL | Prothrombin | 3.4.21.5 | 0.529 | |
| 2a2x | NA9 | Prothrombin | 3.4.21.5 | 0.525 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.524 | |
| 2ziq | 26U | Prothrombin | 3.4.21.5 | 0.515 | |
| 3qdz | PRO_ALA_PRO_ARG | Prothrombin | 3.4.21.5 | 0.515 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.513 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.511 | |
| 3dhk | 23U | Prothrombin | 3.4.21.5 | 0.509 | |
| 4bao | MVF | Prothrombin | 3.4.21.5 | 0.505 | |
| 1c1w | BAH | Prothrombin | 3.4.21.5 | 0.502 | |
| 1vzq | SHY | Prothrombin | 3.4.21.5 | 0.502 | |
| 1w7g | MIU | Prothrombin | 3.4.21.5 | 0.502 | |
| 2zgb | 21U | Prothrombin | 3.4.21.5 | 0.501 | |
| 2uuj | 896 | Prothrombin | 3.4.21.5 | 0.499 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.493 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.492 | |
| 3dux | 64U | Prothrombin | 3.4.21.5 | 0.492 | |
| 1c1u | BAI | Prothrombin | 3.4.21.5 | 0.476 | |
| 3biv | 11U | Prothrombin | 3.4.21.5 | 0.469 | |
| 2bxt | C2D | Prothrombin | 3.4.21.5 | 0.467 | |
| 4hfp | 15U | Prothrombin | 3.4.21.5 | 0.462 | |
| 7kme | ACE_0BN_CHG_PRR | Prothrombin | 3.4.21.5 | 0.461 | |
| 4baq | M4Z | Prothrombin | 3.4.21.5 | 0.456 | |
| 2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.455 | |
| 2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.455 | |
| 4ban | M6S | Prothrombin | 3.4.21.5 | 0.449 | |
| 1nsg | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.447 | |
| 1nsg | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.447 | |
| 4bak | M67 | Prothrombin | 3.4.21.5 | 0.447 |