Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3qj7UMPThymidylate synthase ThyA

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3qj7UMPThymidylate synthase ThyA/1.000
4irrUMPThymidylate synthase/0.559
5by6UMPThymidylate synthase/0.545
1bidUMPThymidylate synthase/0.530
3dgaUMPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.513
2g8aUMPThymidylate synthase/0.509
4h0uUMPThymidylate synthase/0.506
4dpdUMPBifunctional dihydrofolate reductase-thymidylate synthase/0.495
3dg8UMPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.494
1jmgUMPThymidylate synthase/0.493
1ci7UMPThymidylate synthase2.1.1.450.481
4iskUMPThymidylate synthase/0.481
4eb4UMPThymidylate synthase2.1.1.450.479
2vetUMPThymidylate synthase/0.476
4einNOHThymidylate synthase2.1.1.450.470
1njeDCMThymidylate synthase/0.467
4dq1UMPThymidylate synthase/0.466
4e5oUMPThymidylate synthase2.1.1.450.466
2g86UMPThymidylate synthase/0.465
4psgNOHThymidylate synthase/0.460
1jmfUMPThymidylate synthase/0.456
1tsvUMPThymidylate synthase/0.456
2g8dUMPThymidylate synthase/0.455
4fogC2FThymidylate synthase ThyA/0.455
1njaDCMThymidylate synthase/0.453
1tsyUMPThymidylate synthase/0.451
1f4eTPRThymidylate synthase/0.450
1bduDURThymidylate synthase/0.449
2tdmUMPThymidylate synthase/0.447
4xsdUMPThymidylate synthase2.1.1.450.446
1an5CB3Thymidylate synthase/0.444
1njbUMPThymidylate synthase/0.444
2g89UMPThymidylate synthase/0.443
1jmiUMPThymidylate synthase/0.442
4foxUMPThymidylate synthase ThyA/0.442