scPDB - Distribution of Cavity Similarity values of 3n66 entry / Site 2

Distribution of Cavity similarities measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3n66	XFN	Nitric oxide synthase, brain	1.14.13.39

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity
3n66	XFN	Nitric oxide synthase, brain	1.14.13.39	1.000
3n60	XFN	Nitric oxide synthase, brain	1.14.13.39	0.663
3n63	XFN	Nitric oxide synthase, brain	1.14.13.39	0.641
3n65	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.630
3n5x	XFK	Nitric oxide synthase, brain	1.14.13.39	0.582
3n61	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.582
3n62	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.577
3n5w	XFJ	Nitric oxide synthase, brain	1.14.13.39	0.565
4imu	1ET	Nitric oxide synthase, brain	1.14.13.39	0.563
3n61	H4B	Nitric oxide synthase, brain	1.14.13.39	0.553
3n5y	XFL	Nitric oxide synthase, brain	1.14.13.39	0.541
3nlv	3XA	Nitric oxide synthase, brain	1.14.13.39	0.521
1zzu	DP1	Nitric oxide synthase, brain	1.14.13.39	0.515
4imu	H4B	Nitric oxide synthase, brain	1.14.13.39	0.515
4jse	H4B	Nitric oxide synthase, brain	1.14.13.39	0.515
1zzu	H4B	Nitric oxide synthase, brain	1.14.13.39	0.514
3nnz	59W	Nitric oxide synthase, brain	1.14.13.39	0.512
5agl	H4B	Nitric oxide synthase, brain	1.14.13.39	0.511
3n5z	XFM	Nitric oxide synthase, brain	1.14.13.39	0.510
4cx4	HW9	Nitric oxide synthase, brain	1.14.13.39	0.506
3ufv	HW9	Nitric oxide synthase, brain	1.14.13.39	0.504
4jsg	Q10	Nitric oxide synthase, brain	1.14.13.39	0.501
3nny	59R	Nitric oxide synthase, brain	1.14.13.39	0.498
4jsf	QJ4	Nitric oxide synthase, brain	1.14.13.39	0.497
3rqj	Y2B	Nitric oxide synthase, brain	1.14.13.39	0.496
3dqr	H4B	Nitric oxide synthase, brain	1.14.13.39	0.495
3pne	8AX	Nitric oxide synthase, brain	1.14.13.39	0.491
3b3o	JI3	Nitric oxide synthase, brain	1.14.13.39	0.489
3nlj	JRR	Nitric oxide synthase, brain	1.14.13.39	0.489
3nlp	JSS	Nitric oxide synthase, brain	1.14.13.39	0.488
1zzr	DP9	Nitric oxide synthase, brain	1.14.13.39	0.487
4k5d	H4B	Nitric oxide synthase, brain	1.14.13.39	0.485
4cx3	HW8	Nitric oxide synthase, brain	1.14.13.39	0.484
1zzq	DP9	Nitric oxide synthase, brain	1.14.13.39	0.483
3n5z	H4B	Nitric oxide synthase, brain	1.14.13.39	0.483
3jwt	JI5	Nitric oxide synthase, brain	1.14.13.39	0.481
4jsi	Q05	Nitric oxide synthase, brain	1.14.13.39	0.480
1m00	H4B	Nitric oxide synthase, brain	1.14.13.39	0.479
3nlw	3XF	Nitric oxide synthase, brain	1.14.13.39	0.479
3pnf	8BX	Nitric oxide synthase, brain	1.14.13.39	0.477
2hx4	4HX	Nitric oxide synthase, brain	1.14.13.39	0.476
3jta	H4B	Nitric oxide synthase, brain	1.14.13.39	0.475
3ufw	HW0	Nitric oxide synthase, brain	1.14.13.39	0.475
3nlr	JRS	Nitric oxide synthase, brain	1.14.13.39	0.474
3e7t	B14	Nitric oxide synthase, inducible	1.14.13.39	0.473
3tym	08R	Nitric oxide synthase, brain	1.14.13.39	0.473
3ufs	HW6	Nitric oxide synthase, brain	1.14.13.39	0.473
4imt	1EW	Nitric oxide synthase, brain	1.14.13.39	0.473
3nlv	H4B	Nitric oxide synthase, brain	1.14.13.39	0.471
3tym	H4B	Nitric oxide synthase, brain	1.14.13.39	0.471
4k5g	Q13	Nitric oxide synthase, brain	1.14.13.39	0.471
3jx2	JI4	Nitric oxide synthase, brain	1.14.13.39	0.469
3nlq	JRR	Nitric oxide synthase, brain	1.14.13.39	0.469
3nlz	3XD	Nitric oxide synthase, brain	1.14.13.39	0.469
4cx5	HW8	Nitric oxide synthase, brain	1.14.13.39	0.469
1p6k	H4B	Nitric oxide synthase, brain	1.14.13.39	0.466
1zzq	H4B	Nitric oxide synthase, brain	1.14.13.39	0.465
4cx4	H4B	Nitric oxide synthase, brain	1.14.13.39	0.465
3jx5	J14	Nitric oxide synthase, brain	1.14.13.39	0.464
3svp	JK5	Nitric oxide synthase, brain	1.14.13.39	0.464
3ufu	HW8	Nitric oxide synthase, brain	1.14.13.39	0.464
4eux	HW1	Nitric oxide synthase, brain	1.14.13.39	0.464
3b3m	H4B	Nitric oxide synthase, brain	1.14.13.39	0.463
3jx4	J11	Nitric oxide synthase, brain	1.14.13.39	0.463
3b3p	JI7	Nitric oxide synthase, brain	1.14.13.39	0.462
3ufv	H4B	Nitric oxide synthase, brain	1.14.13.39	0.462
4k5d	1Q6	Nitric oxide synthase, brain	1.14.13.39	0.462
3nnz	H4B	Nitric oxide synthase, brain	1.14.13.39	0.461
4imw	1EV	Nitric oxide synthase, brain	1.14.13.39	0.460
3nlp	H4B	Nitric oxide synthase, brain	1.14.13.39	0.459
3nly	3XC	Nitric oxide synthase, brain	1.14.13.39	0.459
3q9a	H4B	Nitric oxide synthase, brain	1.14.13.39	0.459
4k5f	Q14	Nitric oxide synthase, brain	1.14.13.39	0.459
5agk	H4B	Nitric oxide synthase, brain	1.14.13.39	0.459
3tyl	H4B	Nitric oxide synthase, brain	1.14.13.39	0.458
4fw0	H4B	Nitric oxide synthase, brain	1.14.13.39	0.458
4jsg	H4B	Nitric oxide synthase, brain	1.14.13.39	0.458
3rqm	X2E	Nitric oxide synthase, brain	1.14.13.39	0.457
3tyl	AXW	Nitric oxide synthase, brain	1.14.13.39	0.457
4fvz	H4B	Nitric oxide synthase, brain	1.14.13.39	0.457
4k5e	1Q7	Nitric oxide synthase, brain	1.14.13.39	0.456
3jws	JI4	Nitric oxide synthase, brain	1.14.13.39	0.455
3png	8CX	Nitric oxide synthase, brain	1.14.13.39	0.455
2hx4	H4B	Nitric oxide synthase, brain	1.14.13.39	0.454
3ufo	HW4	Nitric oxide synthase, brain	1.14.13.39	0.454
3b3o	H4B	Nitric oxide synthase, brain	1.14.13.39	0.453
3nln	JRS	Nitric oxide synthase, brain	1.14.13.39	0.453
1zzr	H4B	Nitric oxide synthase, brain	1.14.13.39	0.452
2hx3	H4B	Nitric oxide synthase, brain	1.14.13.39	0.452
3b3p	H4B	Nitric oxide synthase, brain	1.14.13.39	0.452
3n5y	H4B	Nitric oxide synthase, brain	1.14.13.39	0.452
3q99	H4B	Nitric oxide synthase, brain	1.14.13.39	0.452
3ufq	H4B	Nitric oxide synthase, brain	1.14.13.39	0.452
1p6j	DP9	Nitric oxide synthase, brain	1.14.13.39	0.451
4jsi	H4B	Nitric oxide synthase, brain	1.14.13.39	0.451
1rs6	H4B	Nitric oxide synthase, brain	1.14.13.39	0.450
3ufq	HW5	Nitric oxide synthase, brain	1.14.13.39	0.450
4jsf	H4B	Nitric oxide synthase, brain	1.14.13.39	0.450
3nlj	H4B	Nitric oxide synthase, brain	1.14.13.39	0.449
4lux	QJ8	Nitric oxide synthase, brain	1.14.13.39	0.449
1rs6	DP2	Nitric oxide synthase, brain	1.14.13.39	0.448
3jt6	H4B	Nitric oxide synthase, brain	1.14.13.39	0.447
3jx3	JI5	Nitric oxide synthase, brain	1.14.13.39	0.447
3ufr	H5W	Nitric oxide synthase, brain	1.14.13.39	0.446
4lux	H4B	Nitric oxide synthase, brain	1.14.13.39	0.446
3rql	X2D	Nitric oxide synthase, brain	1.14.13.39	0.445
3jx0	JI4	Nitric oxide synthase, brain	1.14.13.39	0.444
4fvy	H4B	Nitric oxide synthase, brain	1.14.13.39	0.443
3jwt	H4B	Nitric oxide synthase, brain	1.14.13.39	0.442
3nly	H4B	Nitric oxide synthase, brain	1.14.13.39	0.442
3jt3	H4B	Nitric oxide synthase, brain	1.14.13.39	0.441
4cx5	H4B	Nitric oxide synthase, brain	1.14.13.39	0.441
3jwu	H4B	Nitric oxide synthase, brain	1.14.13.39	0.440
3nlr	H4B	Nitric oxide synthase, brain	1.14.13.39	0.440
4cx3	H4B	Nitric oxide synthase, brain	1.14.13.39	0.440