Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3mdmFJZCholesterol 24-hydroxylase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3mdmFJZCholesterol 24-hydroxylase/1.000
4enhFVXCholesterol 24-hydroxylase/0.621
2q9fC3SCholesterol 24-hydroxylase/0.591
3mdvCL6Cholesterol 24-hydroxylase/0.586
4g7gVFVLanosterol 14-alpha-demethylase/0.462
4tuvCPZCytochrome P450 1191.140.458
4g3jVNTLanosterol 14-alpha-demethylase/0.454