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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3le62BZCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3le62BZCyclin-dependent kinase 22.7.11.221.000
1aq1STUCyclin-dependent kinase 22.7.11.220.593
3lfqA28Cyclin-dependent kinase 22.7.11.220.580
3lfsA07Cyclin-dependent kinase 22.7.11.220.495
2ds11CDCyclin-dependent kinase 22.7.11.220.492
1oirHDYCyclin-dependent kinase 22.7.11.220.489
2bheBRYCyclin-dependent kinase 22.7.11.220.487
2w05FRTCyclin-dependent kinase 22.7.11.220.485
3qwjX6ACyclin-dependent kinase 22.7.11.220.480
2vtrLZBCyclin-dependent kinase 22.7.11.220.478
2r64740Cyclin-dependent kinase 22.7.11.220.474
4erwSTUCyclin-dependent kinase 22.7.11.220.471
1gih1PUCyclin-dependent kinase 22.7.11.220.464
3rkb12ZCyclin-dependent kinase 22.7.11.220.464
3r7iX9ICyclin-dependent kinase 22.7.11.220.461
3lfnA27Cyclin-dependent kinase 22.7.11.220.454
2j9mPY8Cyclin-dependent kinase 22.7.11.220.443
2uznC96Cyclin-dependent kinase 22.7.11.220.442
4fklCK2Cyclin-dependent kinase 22.7.11.220.442
4fkt48KCyclin-dependent kinase 22.7.11.220.440