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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3hl4CDCCholine-phosphate cytidylyltransferase A

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3hl4CDCCholine-phosphate cytidylyltransferase A/1.000
4mvcCDCCholine-phosphate cytidylyltransferase A/0.526
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.463
1szgFNSCytochrome b2, mitochondrial1.1.2.30.455
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.455
2a5hSAML-lysine 2,3-aminomutase5.4.3.20.449
2j2pSC2Ficolin-2/0.447
3coy53HPantothenate synthetase6.3.2.10.447
3v0o4GWHisto-blood group ABO system transferase/0.447
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.445
1x1aSAMC-20 methyltransferase/0.445
4bzbDGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.444
4dya0MFNucleoprotein/0.442
5kwvANPPantothenate synthetase/0.442
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.441
2g1n1IGRenin3.4.23.150.440
3lqsPSZD-alanine aminotransferase2.6.1.210.440
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.440
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.440