sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3gdu | TYR_ARG_PHE | Serine endoprotease DegS | 3.4.21.107 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3gdu | TYR_ARG_PHE | Serine endoprotease DegS | 3.4.21.107 | 1.000 | |
| 3gdv | TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.635 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.470 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.451 | |
| 5itz | GTP | Tubulin alpha-1B chain | / | 0.449 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.448 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.446 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.442 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.441 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.441 | |
| 3suf | SUE | Polyprotein | / | 0.440 |