sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3fp0 | FP0 | 15-O-acetyltransferase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 1.000 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.480 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.474 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.463 | |
| 1u2y | GOX | Pancreatic alpha-amylase | / | 0.461 | |
| 1mew | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.460 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.459 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.459 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.458 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.458 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.457 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.452 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.452 | |
| 1osv | CHC | Bile acid receptor | / | 0.451 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.451 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.450 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.449 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 2j2p | SC2 | Ficolin-2 | / | 0.446 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.446 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.445 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.445 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.443 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.442 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.442 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.442 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.442 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.442 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.442 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.442 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.441 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.441 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.440 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.440 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.440 |