sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3dk9	FAD	Glutathione reductase, mitochondrial	1.8.1.7

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3dk9	FAD	Glutathione reductase, mitochondrial	1.8.1.7	1.000
3dk8	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.876
3dk4	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.814
1bwc	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.621
1gre	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.621
4gr1	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.613
3grs	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.612
1grg	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.610
1grh	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.608
1k4q	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.607
1gsn	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.594
1gra	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.593
2v6o	FAD	Thioredoxin glutathione reductase	/	0.508
2gh5	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.505
3sqp	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.502
3dgz	FAD	Thioredoxin reductase 2, mitochondrial	1.8.1.9	0.501
2nvk	FAD	Thioredoxin reductase 1, mitochondrial	1.8.1.9	0.491
1grb	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.477
2r9z	FAD	Glutathione amide reductase	/	0.454