sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3d2m | COA | Amino-acid acetyltransferase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3d2m | COA | Amino-acid acetyltransferase | / | 1.000 | |
| 2r8v | ACO | Amino-acid acetyltransferase | / | 0.627 | |
| 4gs4 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.466 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.462 | |
| 5kf1 | ACO | Predicted acetyltransferase | / | 0.462 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.462 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.458 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.457 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.456 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.455 | |
| 4el5 | D1M | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.455 | |
| 2jdc | CAO | Probable acetyltransferase | / | 0.453 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.452 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.452 | |
| 4psw | COA | Histone acetyltransferase type B catalytic subunit | / | 0.452 | |
| 4u9v | ACO | N-alpha-acetyltransferase 40 | 2.3.1 | 0.451 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.450 | |
| 2jdd | ACO | Probable acetyltransferase | / | 0.449 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.449 | |
| 3nta | COA | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.447 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.447 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 3exn | ACO | Probable acetyltransferase | / | 0.446 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.444 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.443 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.441 | |
| 4zm6 | ACO | N-acetyl-beta-D glucosaminidase | / | 0.441 | |
| 5f54 | TMP | Single-stranded-DNA-specific exonuclease | / | 0.441 | |
| 3fpz | AHZ | Thiamine thiazole synthase | / | 0.440 |