Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2xpuTDCTetracycline repressor protein class D

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2xpuTDCTetracycline repressor protein class D/1.000
5fklTDCTetracycline repressor protein class D/0.651
2vkeTACTetracycline repressor protein class D/0.612
4auxXTCTetracycline repressor protein class D/0.598
2xpwOTCTetracycline repressor protein class D/0.566
2trtTACTetracycline repressor protein class D/0.561
2xpvMIYTetracycline repressor protein class D/0.558
5fkmTDCTetracycline repressor protein class D/0.548
1orkATCTetracycline repressor protein class D/0.546
2o7oDXTTetracycline repressor protein class D/0.541
2fj1CTCTetracycline repressor protein class D/0.531
2x9dITCTetracycline repressor protein class D/0.523
2xb5I7TTetracycline repressor protein class D/0.516
4d7mTDCTetracycline repressor protein class D/0.504
4v2gITCTetracycline repressor protein class D/0.490
5fkoTDCTetracycline repressor protein class D/0.485
2tctCTCTetracycline repressor protein class D/0.477
4b3aTACTetracycline repressor protein class D/0.477
4abzT1CTetracycline repressor protein class D/0.476
4b1rITCTetracycline repressor protein class D/0.466
2xrlDXTTetracycline repressor protein class D/0.452