sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2xpc | 051 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2xpc | 051 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 1.000 | |
| 2uuo | LK3 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.634 | |
| 2jfh | LK1 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.611 | |
| 2vte | IK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.595 | |
| 2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.593 | |
| 1uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.581 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.521 | |
| 2y67 | N21 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.502 | |
| 2jfg | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.484 | |
| 2y66 | N04 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.481 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.477 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.475 | |
| 2uup | LK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.471 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.471 | |
| 1d2h | SAH | Glycine N-methyltransferase | 2.1.1.20 | 0.469 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.460 | |
| 4wxf | PLG | Serine hydroxymethyltransferase | / | 0.457 | |
| 4rv9 | SAH | D-mycarose 3-C-methyltransferase | / | 0.456 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.455 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.449 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 3eks | CY9 | Actin-5C | / | 0.448 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.448 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.447 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.445 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.444 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.443 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.442 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 3mz9 | BHN | Nickel-binding periplasmic protein | / | 0.441 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.440 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.440 | |
| 3dr7 | GPD | GDP-perosamine synthase | / | 0.440 | |
| 4wxg | 2BO | Serine hydroxymethyltransferase | / | 0.440 |