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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2wbaFADTrypanothione reductase1.8.1.12

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2wbaFADTrypanothione reductase1.8.1.121.000
2hqmFADGlutathione reductase1.8.1.70.539
1gxfFADTrypanothione reductase1.8.1.120.526
1fecFADTrypanothione reductase1.8.1.120.504
3dgzFADThioredoxin reductase 2, mitochondrial1.8.1.90.502
3sqpFADGlutathione reductase, mitochondrial1.8.1.70.501
1bzlFADTrypanothione reductase1.8.1.120.493
2jk6FADTrypanothione reductase/0.492
1k4qFADGlutathione reductase, mitochondrial1.8.1.70.487
1tytFADTrypanothione reductase1.8.1.120.484
4dnaFADProbable glutathione reductase/0.482
4nevFADTrypanothione reductase/0.473
4la1FADThioredoxin glutathione reductase/0.469
4j56FADThioredoxin reductase 21.8.1.90.459