Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2r9rNAPVoltage-gated potassium channel subunit beta-2

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2r9rNAPVoltage-gated potassium channel subunit beta-2/1.000
3lnmNAPVoltage-gated potassium channel subunit beta-2/0.599
4jtcNAPVoltage-gated potassium channel subunit beta-2/0.598
4aubNAPL-glyceraldehyde 3-phosphate reductase1.1.10.565
4jtaNAPVoltage-gated potassium channel subunit beta-2/0.556
4jtdNAPVoltage-gated potassium channel subunit beta-2/0.544
1lqaNDPProtein tas/0.515
2clpNDPAflatoxin B1 aldehyde reductase member 3/0.508
1az2NAPAldose reductase1.1.1.210.475
3v36NAPAldose reductase1.1.1.210.475
2iq0NAPAldose reductase1.1.1.210.461
1pz1NAPGeneral stress protein 69/0.456
4pmjNAPPutative oxidoreductase/0.456
1og6NAPOxidoreductase YdhF10.455
2pevNDPAldose reductase1.1.1.210.455
3h7uNAPNADPH-dependent aldo-keto reductase, chloroplastic/0.450
1ah4NAPAldose reductase1.1.1.210.449
1x96NAPAldose reductase1.1.1.210.449
4g5dNDPProstaglandin F synthase1.1.1.1880.448
3o3rNAPAldose reductase-related protein 11.1.1.210.446
2j8tNAPAldose reductase1.1.1.210.445
3v0tATRPerakine reductase1.1.1.3170.445
2acuNAPAldose reductase1.1.1.210.444
2acqNAPAldose reductase1.1.1.210.441
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.440