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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2q9fC3SCholesterol 24-hydroxylase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2q9fC3SCholesterol 24-hydroxylase/1.000
3mdvCL6Cholesterol 24-hydroxylase/0.548
4enhFVXCholesterol 24-hydroxylase/0.538
3mdmFJZCholesterol 24-hydroxylase/0.508
3p3zP3ZPutative cytochrome P450/0.485
4g3jVNTLanosterol 14-alpha-demethylase/0.467
4tuvCPZCytochrome P450 1191.140.453
4g7gVFVLanosterol 14-alpha-demethylase/0.449
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.440