sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2hb7 | O1C | Vitamin D3 receptor |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2hb7 | O1C | Vitamin D3 receptor | / | 1.000 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.825 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.729 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.719 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.715 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.711 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.700 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.699 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.696 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.688 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.680 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.676 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.674 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.674 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.672 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.671 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.670 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.670 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.670 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.670 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.666 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.657 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.653 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.653 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.652 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.650 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.649 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.647 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.646 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.646 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.645 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.643 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.642 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.642 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.640 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.639 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.638 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.638 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.637 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.637 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.635 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.635 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.635 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.633 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.631 | |
| 3m7r | VDX | Vitamin D3 receptor | / | 0.629 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.628 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.626 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.626 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.626 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.623 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.622 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.618 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.618 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.618 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.616 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.615 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.614 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.610 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.609 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.607 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.602 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.600 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.599 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.594 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.590 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.581 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.580 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.576 | |
| 4g2i | 0VQ | Vitamin D3 receptor | / | 0.574 | |
| 3w5q | 3KL | Vitamin D3 receptor | / | 0.547 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.474 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.472 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.471 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.464 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.462 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.458 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.457 | |
| 1ie4 | T44 | Transthyretin | / | 0.455 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.455 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.455 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.453 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.453 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.449 | |
| 1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.448 | |
| 3oqu | A8S | Abscisic acid receptor PYL9 | / | 0.447 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.446 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.443 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.442 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.442 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4l9k | EHF | Serum albumin | / | 0.442 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.441 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.441 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.440 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.440 |