sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2g9v	IFM	Glycogen phosphorylase, muscle form	2.4.1.1

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
2g9v	IFM	Glycogen phosphorylase, muscle form	2.4.1.1	1.000
2g9u	G27	Glycogen phosphorylase, muscle form	2.4.1.1	0.577
2qn3	F55	Glycogen phosphorylase, muscle form	2.4.1.1	0.493
2qn7	HBZ	Glycogen phosphorylase, muscle form	2.4.1.1	0.490
3mt8	17T	Glycogen phosphorylase, muscle form	2.4.1.1	0.481
1noi	NTZ	Glycogen phosphorylase, muscle form	2.4.1.1	0.471
2qln	F59	Glycogen phosphorylase, muscle form	2.4.1.1	0.471
4eke	D1I	Glycogen phosphorylase, muscle form	2.4.1.1	0.469
3l7d	DK5	Glycogen phosphorylase, muscle form	2.4.1.1	0.449