scPDB - Distribution of Cavity Similarity values of 2fz9 entry / Site 1

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2fz9	ZST	Aldose reductase	1.1.1.21

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity
2fz9	ZST	Aldose reductase	1.1.1.21	1.000
2dv0	ZST	Aldose reductase	1.1.1.21	0.778
2hv5	ZST	Aldose reductase	1.1.1.21	0.748
2pdx	ZST	Aldose reductase	1.1.1.21	0.732
2fz8	ZST	Aldose reductase	1.1.1.21	0.683
1z89	62P	Aldose reductase	1.1.1.21	0.668
3m4h	388	Aldose reductase	1.1.1.21	0.650
2ikj	393	Aldose reductase	1.1.1.21	0.649
3m64	393	Aldose reductase	1.1.1.21	0.641
4gca	2X9	Aldose reductase	1.1.1.21	0.632
3lql	LDT	Aldose reductase	1.1.1.21	0.631
3mb9	ZST	Aldose reductase	1.1.1.21	0.626
3lbo	LDT	Aldose reductase	1.1.1.21	0.624
2pdu	393	Aldose reductase	1.1.1.21	0.620
1t40	ID5	Aldose reductase	1.1.1.21	0.607
2pdg	47D	Aldose reductase	1.1.1.21	0.595
1z3n	3NA	Aldose reductase	1.1.1.21	0.585
1t41	ID5	Aldose reductase	1.1.1.21	0.584
2iki	388	Aldose reductase	1.1.1.21	0.584
2fzd	TOL	Aldose reductase	1.1.1.21	0.580
2pdp	393	Aldose reductase	1.1.1.21	0.579
1iei	ZES	Aldose reductase	1.1.1.21	0.563
2pdh	47D	Aldose reductase	1.1.1.21	0.554
2ikh	LIT	Aldose reductase	1.1.1.21	0.552
3len	ZST	Aldose reductase	1.1.1.21	0.551
3t42	3T4	Aldose reductase	1.1.1.21	0.551
2hvo	ZST	Aldose reductase	1.1.1.21	0.549
1pwl	BFI	Aldose reductase	1.1.1.21	0.547
2i16	LDT	Aldose reductase	1.1.1.21	0.546
3lz5	LDT	Aldose reductase	1.1.1.21	0.546
2pzn	393	Aldose reductase	1.1.1.21	0.539
2pdf	ZST	Aldose reductase	1.1.1.21	0.538
4yu1	53N	Aldose reductase	1.1.1.21	0.537
2pdb	ZST	Aldose reductase	1.1.1.21	0.535
2pdy	FID	Aldose reductase	1.1.1.21	0.533
3g5e	Q74	Aldose reductase	1.1.1.21	0.532
2qxw	LDT	Aldose reductase	1.1.1.21	0.527
3ghr	LDT	Aldose reductase	1.1.1.21	0.526
2pd5	ZST	Aldose reductase	1.1.1.21	0.523
2pdl	TOL	Aldose reductase	1.1.1.21	0.518
3m0i	ZST	Aldose reductase	1.1.1.21	0.518
3mc5	393	Aldose reductase	1.1.1.21	0.515
2iqd	LPA	Aldose reductase	1.1.1.21	0.513
2pdc	393	Aldose reductase	1.1.1.21	0.509
1us0	LDT	Aldose reductase	1.1.1.21	0.508
2inz	OHP	Aldose reductase	1.1.1.21	0.507
3ghu	LDT	Aldose reductase	1.1.1.21	0.503
3ghs	LDT	Aldose reductase	1.1.1.21	0.500
2pdn	47D	Aldose reductase	1.1.1.21	0.494
2dux	ZST	Aldose reductase	1.1.1.21	0.493
1frb	ZST	Aldose reductase-related protein 2	/	0.490
3ght	LDT	Aldose reductase	1.1.1.21	0.481
2pdq	47D	Aldose reductase	1.1.1.21	0.465
2duz	ZST	Aldose reductase	1.1.1.21	0.463
2f2k	TGG	Aldose reductase	1.1.1.21	0.462
3ld5	LDT	Aldose reductase	1.1.1.21	0.462
2i17	LDT	Aldose reductase	1.1.1.21	0.457
4ga8	SBI	Aldo-keto reductase family 1 member B10	1.1.1	0.456
1ps9	MDE	2,4-dienoyl-CoA reductase	1.3.1.34	0.451
2c1z	KMP	Anthocyanidin 3-O-glucosyltransferase 2	2.4.1.115	0.451
3g49	3G4	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.451
1ah3	TOL	Aldose reductase	1.1.1.21	0.448
4ey6	GNT	Acetylcholinesterase	3.1.1.7	0.444
4j7h	TRH	PCZA361.3	/	0.444
2zs9	ADP	Pantothenate kinase	2.7.1.33	0.443
4ara	C56	Acetylcholinesterase	3.1.1.7	0.443
3sfy	3FY	Uncharacterized protein	/	0.442
3u57	DH8	Raucaffricine-O-beta-D-glucosidase	3.2.1.125	0.442
1mkd	ZAR	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.440