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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2f0y3MNProtein farnesyltransferase subunit beta2.5.1.58

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2f0y3MNProtein farnesyltransferase subunit beta2.5.1.581.000
1ni1HFPProtein farnesyltransferase subunit beta2.5.1.580.665
3e30ED4Protein farnesyltransferase subunit beta2.5.1.580.655
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.649
2r2lPB9Protein farnesyltransferase subunit beta2.5.1.580.647
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.622
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.622
1o1s1NHProtein farnesyltransferase subunit beta2.5.1.580.622
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.615
1mzcBNEProtein farnesyltransferase subunit beta2.5.1.580.614
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.611
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.611
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.610
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.580.608
3q7fED2Uncharacterized protein/0.603
2iejS48Protein farnesyltransferase subunit beta2.5.1.580.597
1jcq739Protein farnesyltransferase subunit beta2.5.1.580.596
1ld8U49Protein farnesyltransferase subunit beta2.5.1.580.596
1ld7U66Protein farnesyltransferase subunit beta2.5.1.580.593
3sfy3FYUncharacterized protein/0.592
1s63778Protein farnesyltransferase subunit beta2.5.1.580.587
1sa4JANProtein farnesyltransferase subunit beta2.5.1.580.580
1o1t2NHProtein farnesyltransferase subunit beta2.5.1.580.575
4gtr7TRProtein farnesyltransferase subunit beta2.5.1.580.570
3kslSZHProtein farnesyltransferase subunit beta2.5.1.580.553
3pz43PZProtein farnesyltransferase subunit beta2.5.1.580.547
1n4sCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.494
1s64778Geranylgeranyl transferase type-1 subunit beta2.5.1.590.467
3hxbBD5Geranylgeranyl transferase type-2 subunit beta2.5.1.600.457