Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2ek2SAHDiphthine synthase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2ek2SAHDiphthine synthase/1.000
2z6rSAHDiphthine synthase/0.816
2e4nSAHDiphthine synthase/0.791
2e17SAHDiphthine synthase/0.788
2owkSAHDiphthine synthase/0.762
2eh2SAHDiphthine synthase/0.761
2pb6SAHDiphthine synthase/0.758
2emuSAHDiphthine synthase/0.739
2eh5SAHDiphthine synthase/0.734
2hutSAHDiphthine synthase/0.730
2owuSAHDiphthine synthase/0.728
2ehlSAHDiphthine synthase/0.725
2ed5SAHDiphthine synthase/0.721
2emrSAHDiphthine synthase/0.713
2huvSAHDiphthine synthase/0.710
2ek3SAHDiphthine synthase/0.708
2e15SAHDiphthine synthase/0.707
2el0SAHDiphthine synthase/0.707
2eldSAHDiphthine synthase/0.707
1wngSAHDiphthine synthase/0.706
2el3SAHDiphthine synthase/0.705
2e8rSAHDiphthine synthase/0.701
2dekSAHDiphthine synthase/0.700
2eeqSAHDiphthine synthase/0.698
2dsiSAHDiphthine synthase/0.696
2e07SAHDiphthine synthase/0.696
2dsgSAHDiphthine synthase/0.693
2ek7SAHDiphthine synthase/0.692
2ek4SAHDiphthine synthase/0.689
2p6lSAHDiphthine synthase/0.686
2e8qSAHDiphthine synthase/0.685
2eh4SAHDiphthine synthase/0.683
2eniSAHDiphthine synthase/0.680
2dxwSAHDiphthine synthase/0.675
2huxSAHDiphthine synthase/0.675
2pciSAHDiphthine synthase/0.674
2owgSAHDiphthine synthase/0.666
2e8sSAHDiphthine synthase/0.665
2p5fSAHDiphthine synthase/0.664
2dv5SAHDiphthine synthase/0.659
1vceSAHDiphthine synthase/0.655
2dv4SAHDiphthine synthase/0.654
2pb4SAHDiphthine synthase/0.654
2eleSAHDiphthine synthase/0.653
2p6dSAHDiphthine synthase/0.652
2e8hSAHDiphthine synthase/0.651
2en5SAHDiphthine synthase/0.651
2huqSAHDiphthine synthase/0.650
2dxvSAHDiphthine synthase/0.649
2pcmSAHDiphthine synthase/0.649
2dv3SAHDiphthine synthase/0.648
2ejjSAHDiphthine synthase/0.646
2p5cSAHDiphthine synthase/0.644
2dv7SAHDiphthine synthase/0.643
2e16SAHDiphthine synthase/0.638
2owvSAHDiphthine synthase/0.634
2ejkSAHDiphthine synthase/0.630
2pcaSAHDiphthine synthase/0.628
2ekaSAHDiphthine synthase/0.626
2p9dSAHDiphthine synthase/0.624
2p6kSAHDiphthine synthase/0.622
2pcgSAHDiphthine synthase/0.622
2eglSAHDiphthine synthase/0.621
2hr8SAHDiphthine synthase/0.620
2p6iSAHDiphthine synthase/0.619
2dxxSAHDiphthine synthase/0.618
2pb5SAHDiphthine synthase/0.617
2e7rSAHDiphthine synthase/0.612
2pchSAHDiphthine synthase/0.610
2ed3SAHDiphthine synthase/0.608
2p2xSAHDiphthine synthase/0.607
2egsSAHDiphthine synthase/0.583
2e08SAHDiphthine synthase/0.580
2pckSAHDiphthine synthase/0.578
2dshSAHDiphthine synthase/0.565
2owfSAHDiphthine synthase/0.552
2egbSAHDiphthine synthase/0.531
2ejzSAHDiphthine synthase/0.521
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.505
3up5FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.482
1f8fNADBenzyl alcohol dehydrogenase/0.473
3ig6438Urokinase-type plasminogen activator3.4.21.730.472
3ut5LOCTubulin beta chain/0.469
4hbgNDP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.469
1tqf32PBeta-secretase 13.4.23.460.468
1xe55FEPlasmepsin-23.4.23.390.464
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.464
2q4bNAPUncharacterized protein At5g02240/0.463
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.460
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.459
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.459
4f5yC2EStimulator of interferon genes protein/0.459
1bsvNDPGDP-L-fucose synthase/0.458
2b8l5HABeta-secretase 13.4.23.460.458
2xhd7T9Glutamate receptor 2/0.458
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.457
2po7CHDFerrochelatase, mitochondrial4.99.1.10.455
4bfzZVZPantothenate kinase2.7.1.330.455
2znnS44Peroxisome proliferator-activated receptor alpha/0.454
3kjiADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.454
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.454
3ieuGDPGTPase Era/0.453
4wriOKAOkadaic acid binding protein 2-alpha/0.453
1fxsNAPGDP-L-fucose synthase/0.452
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.452
3u33FADPutative acyl-CoA dehydrogenase AidB1.3.990.450
4ougLP5Peptidoglycan recognition protein 1/0.450
2a94AP0L-lactate dehydrogenase1.1.1.270.449
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.449
4q71FADBifunctional protein PutA/0.449
2fznFADBifunctional protein PutA1.5.5.20.447
2gjlFMNNitronate monooxygenase1.13.12.160.447
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.447
3triNAPPyrroline-5-carboxylate reductase/0.447
1tj0FADBifunctional protein PutA1.5.5.20.446
2w06FRVCyclin-dependent kinase 22.7.11.220.446
3a3gDLZLumazine protein/0.445
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.444
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.444
2ifaFMNUncharacterized protein/0.444
2pb2PLPAcetylornithine/succinyldiaminopimelate aminotransferase2.6.1.110.444
2g8yNADHydroxycarboxylate dehydrogenase B/0.443
2gjnFMNNitronate monooxygenase1.13.12.160.443
3q5lKX2Heat shock protein 83-1/0.443
4jloADPAdenylate kinase/0.443
1lbcCYZGlutamate receptor 2/0.442
1rb3MTXDihydrofolate reductase1.5.1.30.442
1x1cSAHC-20 methyltransferase/0.442
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.442
5dp2NAPCurF/0.442
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.441
1hygNAPL-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))/0.441
2rhgIGPTryptophan synthase alpha chain/0.441
3w6hAZMCarbonic anhydrase 14.2.1.10.440
3zh8C58Protein kinase C iota type2.7.11.130.440