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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2ds11CDCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2ds11CDCyclin-dependent kinase 22.7.11.221.000
3lfqA28Cyclin-dependent kinase 22.7.11.220.579
3le62BZCyclin-dependent kinase 22.7.11.220.561
2vtrLZBCyclin-dependent kinase 22.7.11.220.531
2b53D23Cyclin-dependent kinase 22.7.11.220.517
2a0cCK9Cyclin-dependent kinase 22.7.11.220.516
3lfnA27Cyclin-dependent kinase 22.7.11.220.506
4fkv61KCyclin-dependent kinase 22.7.11.220.505
1aq1STUCyclin-dependent kinase 22.7.11.220.498
3r9dX6BCyclin-dependent kinase 22.7.11.220.498
4ek816KCyclin-dependent kinase 22.7.11.220.494
1oirHDYCyclin-dependent kinase 22.7.11.220.491
1pxlCK4Cyclin-dependent kinase 22.7.11.220.485
1y91CT9Cyclin-dependent kinase 22.7.11.220.485
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.485
3rk909ZCyclin-dependent kinase 22.7.11.220.484
3qwjX6ACyclin-dependent kinase 22.7.11.220.483
3r1yX76Cyclin-dependent kinase 22.7.11.220.483
3r83Z14Cyclin-dependent kinase 22.7.11.220.482
3rpo24ZCyclin-dependent kinase 22.7.11.220.482
3rk708ZCyclin-dependent kinase 22.7.11.220.481
1ykr628Cyclin-dependent kinase 22.7.11.220.480
4fkg4CKCyclin-dependent kinase 22.7.11.220.476
1g5sI17Cyclin-dependent kinase 22.7.11.220.475
2r3jSCJCyclin-dependent kinase 22.7.11.220.475
4fklCK2Cyclin-dependent kinase 22.7.11.220.473
2bheBRYCyclin-dependent kinase 22.7.11.220.472
2a4lRRCCyclin-dependent kinase 22.7.11.220.471
3rni21ZCyclin-dependent kinase 22.7.11.220.471
2w05FRTCyclin-dependent kinase 22.7.11.220.469
1oitHDTCyclin-dependent kinase 22.7.11.220.468
3qu0X40Cyclin-dependent kinase 22.7.11.220.464
4erwSTUCyclin-dependent kinase 22.7.11.220.463
4fks46KCyclin-dependent kinase 22.7.11.220.463
4ek610KCyclin-dependent kinase 22.7.11.220.458
2b52D42Cyclin-dependent kinase 22.7.11.220.455
2c6kDT2Cyclin-dependent kinase 22.7.11.220.453
3iggEFQCyclin-dependent kinase 22.7.11.220.453
3r8vZ62Cyclin-dependent kinase 22.7.11.220.452
3r8lZ30Cyclin-dependent kinase 22.7.11.220.449
1pxoCK7Cyclin-dependent kinase 22.7.11.220.448
2uznC96Cyclin-dependent kinase 22.7.11.220.447
3r7iX9ICyclin-dependent kinase 22.7.11.220.446
2xmyCDKCyclin-dependent kinase 22.7.11.220.445
4fki09KCyclin-dependent kinase 22.7.11.220.444
2exmZIPCyclin-dependent kinase 22.7.11.220.442
3qqlX03Cyclin-dependent kinase 22.7.11.220.441
4ez50RSCyclin-dependent kinase 62.7.11.220.441
2r64740Cyclin-dependent kinase 22.7.11.220.440
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.440