Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1zuaTOLAldo-keto reductase family 1 member B101.1.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1zuaTOLAldo-keto reductase family 1 member B101.1.11.000
4wevSUZAldo-keto reductase family 1 member B101.1.10.563
2pdfZSTAldose reductase1.1.1.210.520
2fzdTOLAldose reductase1.1.1.210.519
2pdlTOLAldose reductase1.1.1.210.507
2pdmZSTAldose reductase1.1.1.210.507
2hvoZSTAldose reductase1.1.1.210.499
2pdh47DAldose reductase1.1.1.210.497
2pdiZSTAldose reductase1.1.1.210.491
2hvnZSTAldose reductase1.1.1.210.487
2fzbTOLAldose reductase1.1.1.210.481
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.479
1ah3TOLAldose reductase1.1.1.210.473
2pdg47DAldose reductase1.1.1.210.472
3ghtLDTAldose reductase1.1.1.210.446
2pd9FIDAldose reductase1.1.1.210.444
1ekoI84Aldose reductase1.1.1.210.443
4gabFIDAldo-keto reductase family 1 member B101.1.10.442
3v94WYQPhosphodiesterase/0.441
3zkuHCVIsopenicillin N synthase1.21.3.10.440