Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1z5wGTPTubulin gamma-1 chain

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1z5wGTPTubulin gamma-1 chain/1.000
1z5vGSPTubulin gamma-1 chain/0.717
4i8x6P3L-lactate dehydrogenase A chain1.1.1.270.476
3of4FMNNitroreductase/0.468
1s7gNADNAD-dependent protein deacylase 2/0.464
4af7FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.457
2g8yNADHydroxycarboxylate dehydrogenase B/0.456
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.451
1vjtNADAlpha-glucosidase, putative/0.450
3gb4D3MDdmC/0.449
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.448
2zshGA3Gibberellin receptor GID1A30.448
1fwmCB3Thymidylate synthase/0.447
4b4w9L9Bifunctional protein FolD/0.446
3nmpPYVAbscisic acid receptor PYL2/0.445
4uajFADNa(+)-translocating NADH-quinone reductase subunit F/0.445
2yltNAPPhenylacetone monooxygenase1.14.13.920.444
3up5NAP2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.444
5dp2NAPCurF/0.444
2ociTYCValacyclovir hydrolase3.10.442
1tysTMPThymidylate synthase/0.441
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.441
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.440