sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1y52 | BTN | Avidin-related protein 4/5 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1y52 | BTN | Avidin-related protein 4/5 | / | 1.000 | |
| 4bcs | BTN | Avidin-related protein 4/5 | / | 0.619 | |
| 2uyw | BTN | Avd protein | / | 0.603 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.598 | |
| 2fhl | BNI | Avidin-related protein 4/5 | / | 0.569 | |
| 2rtg | BTN | Streptavidin | / | 0.549 | |
| 1mk5 | BTN | Streptavidin | / | 0.547 | |
| 2uz2 | BTN | Avd protein | / | 0.545 | |
| 2izg | BTN | Streptavidin | / | 0.541 | |
| 2avi | BTN | Avidin | / | 0.537 | |
| 2izl | IMI | Streptavidin | / | 0.537 | |
| 2rti | GLL | Streptavidin | / | 0.527 | |
| 1lcw | SHM | Streptavidin | / | 0.525 | |
| 2rtf | BTN | Streptavidin | / | 0.523 | |
| 2rto | IMI | Streptavidin | / | 0.521 | |
| 1stp | BTN | Streptavidin | / | 0.520 | |
| 3ry2 | BTN | Streptavidin | / | 0.518 | |
| 4gda | BTN | Streptavidin | / | 0.515 | |
| 2izh | BTN | Streptavidin | / | 0.514 | |
| 2rtp | IMI | Streptavidin | / | 0.514 | |
| 1avd | BTN | Avidin | / | 0.511 | |
| 1swt | BTN | Streptavidin | / | 0.511 | |
| 1srj | NAB | Streptavidin | / | 0.509 | |
| 2rtq | IMI | Streptavidin | / | 0.509 | |
| 2rtr | IMI | Streptavidin | / | 0.509 | |
| 1srg | MHB | Streptavidin | / | 0.505 | |
| 4bx7 | B4F | Streptavidin | / | 0.502 | |
| 4dne | DTB | Streptavidin | / | 0.501 | |
| 1sri | DMB | Streptavidin | / | 0.499 | |
| 2rtd | BTN | Streptavidin | / | 0.499 | |
| 2izf | BTN | Streptavidin | / | 0.497 | |
| 2rtn | IMI | Streptavidin | / | 0.496 | |
| 1sre | HAB | Streptavidin | / | 0.493 | |
| 1srf | MTB | Streptavidin | / | 0.489 | |
| 2rte | BTN | Streptavidin | / | 0.489 | |
| 2y3f | BTN | Streptavidin | / | 0.489 | |
| 1df8 | BTN | Streptavidin | / | 0.486 | |
| 1i9h | BNI | Streptavidin | / | 0.485 | |
| 2c4i | BTN | Avidin | / | 0.484 | |
| 1srh | MOB | Streptavidin | / | 0.482 | |
| 1lcz | BH7 | Streptavidin | / | 0.479 | |
| 3wzn | BTN | Streptavidin | / | 0.479 | |
| 2izk | GLL | Streptavidin | / | 0.477 | |
| 3wyq | BTN | Streptavidin | / | 0.477 | |
| 1rxh | BNI | Streptavidin | / | 0.475 | |
| 4z28 | BTN | Hoefavidin | / | 0.471 | |
| 1nc9 | IMI | Streptavidin | / | 0.468 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.466 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.466 | |
| 3rdq | DTB | Streptavidin | / | 0.461 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.458 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.451 | |
| 2rtk | GLL | Streptavidin | / | 0.451 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.449 | |
| 1dfo | PLG | Serine hydroxymethyltransferase | 2.1.2.1 | 0.448 | |
| 2rtm | IMI | Streptavidin | / | 0.448 | |
| 1euy | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.446 | |
| 4epq | 0RR | Poly(ADP-ribose) glycohydrolase | / | 0.446 | |
| 2zsc | BTN | Tamavidin2 | / | 0.445 | |
| 1s0j | MUS | Trans-sialidase | / | 0.443 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.443 | |
| 3upr | 1KX | HLA class I histocompatibility antigen, B-57 alpha chain | / | 0.443 | |
| 1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.441 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.441 | |
| 1luq | BTN | Streptavidin | / | 0.440 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.440 |