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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1wy7SAHUncharacterized protein

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1wy7SAHUncharacterized protein/1.000
1nw3SAMHistone-lysine N-methyltransferase, H3 lysine-79 specific2.1.1.430.490
2zifSAMMethyltransferase/0.488
2f8lSAMLmo1582 protein/0.478
3qowSAMHistone-lysine N-methyltransferase, H3 lysine-79 specific2.1.1.430.476
1sg9SAMRelease factor glutamine methyltransferase2.1.1.2970.461
5bxySAHPutative RNA methylase family UPF0020/0.456
5epeSAHUncharacterized protein/0.456
3uj8SFGPhosphoethanolamine N-methyltransferase/0.454
3grrSAHProbable ribosomal RNA small subunit methyltransferase A/0.453
3q87SAMN6 ADENINE SPECIFIC DNA METHYLASE (METHYLTRANSFERASE SUPERFAMILY)/0.453
1nv8SAMRelease factor glutamine methyltransferase2.1.1.2970.452
4blwSAHRibosomal RNA large subunit methyltransferase J/0.451
1nbiSAMGlycine N-methyltransferase2.1.1.200.448
1qanSAHrRNA adenine N-6-methyltransferase2.1.1.1840.447
3uj7SAMPhosphoethanolamine N-methyltransferase/0.447
4obwSAM2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial/0.445
1nw5SAMModification methylase RsrI2.1.1.720.443
3tljSAHUncharacterized protein/0.443
1vq1SAMRelease factor glutamine methyltransferase2.1.1.2970.442
4uy6SAHHistidine N-alpha-methyltransferase/0.442
9mhtSAHModification methylase HhaI2.1.1.370.441
1kiaSAMGlycine N-methyltransferase2.1.1.200.440