sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1mma | ADP | Myosin-2 heavy chain |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1mma | ADP | Myosin-2 heavy chain | / | 1.000 | |
| 3myk | ANP | Myosin-2 heavy chain | / | 0.571 | |
| 1fmw | ATP | Myosin-2 heavy chain | / | 0.541 | |
| 1l2o | ADP | Myosin heavy chain, striated muscle | / | 0.540 | |
| 1b7t | ADP | Myosin heavy chain, striated muscle | / | 0.511 | |
| 4pk4 | ADP | Unconventional myosin-VI | / | 0.511 | |
| 4pjj | ADP | Unconventional myosin-VI | / | 0.508 | |
| 1jx2 | ADP | Myosin-2 heavy chain | / | 0.501 | |
| 4db1 | ANP | Myosin-7 | / | 0.476 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.459 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 3w5u | FAD | Ferredoxin | / | 0.446 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.444 |