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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1m8dH4BNitric oxide synthase, inducible1.14.13.39

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
1m8dH4BNitric oxide synthase, inducible1.14.13.391.000
2y37H4BNitric oxide synthase, inducible1.14.13.390.639
1qomH4BNitric oxide synthase, inducible1.14.13.390.627
1m8iH4BNitric oxide synthase, inducible1.14.13.390.620
3e67H4BNitric oxide synthase, inducible1.14.13.390.603
1m9tH4BNitric oxide synthase, inducible1.14.13.390.597
3e6oH4BNitric oxide synthase, inducible1.14.13.390.584
3e6tH4BNitric oxide synthase, inducible1.14.13.390.582
3dwjH4BNitric oxide synthase, inducible1.14.13.390.580
1r35H4BNitric oxide synthase, inducible1.14.13.390.579
1m8eH4BNitric oxide synthase, inducible1.14.13.390.577
1m8hH4BNitric oxide synthase, inducible1.14.13.390.574
3nw2H4BNitric oxide synthase, inducible1.14.13.390.563
3e7gH4BNitric oxide synthase, inducible1.14.13.390.559
1om5H4BNitric oxide synthase, brain1.14.13.390.553
1qw5H4BNitric oxide synthase, inducible1.14.13.390.548
3b3pH4BNitric oxide synthase, brain1.14.13.390.548
3b3mH4BNitric oxide synthase, brain1.14.13.390.543
4k5dH4BNitric oxide synthase, brain1.14.13.390.540
1k2tH4BNitric oxide synthase, brain1.14.13.390.539
3pngH4BNitric oxide synthase, brain1.14.13.390.538
4k5eH4BNitric oxide synthase, brain1.14.13.390.536
1m00H4BNitric oxide synthase, brain1.14.13.390.535
2hx4H4BNitric oxide synthase, brain1.14.13.390.535
3ufvH4BNitric oxide synthase, brain1.14.13.390.535
3tylH4BNitric oxide synthase, brain1.14.13.390.534
3ufsH4BNitric oxide synthase, brain1.14.13.390.534
1p6jH4BNitric oxide synthase, brain1.14.13.390.533
1k2uH4BNitric oxide synthase, brain1.14.13.390.532
3nnzH4BNitric oxide synthase, brain1.14.13.390.532
1rs6H4BNitric oxide synthase, brain1.14.13.390.531
3nlvH4BNitric oxide synthase, brain1.14.13.390.531
4ux6H4BNitric oxide synthase, inducible1.14.13.390.531
2nodH4BNitric oxide synthase, inducible1.14.13.390.530
3ufqH4BNitric oxide synthase, brain1.14.13.390.528
4jsgH4BNitric oxide synthase, brain1.14.13.390.528
3b3oH4BNitric oxide synthase, brain1.14.13.390.527
3n5zH4BNitric oxide synthase, brain1.14.13.390.527
3pnfH4BNitric oxide synthase, brain1.14.13.390.527
1vafH4BNitric oxide synthase, inducible1.14.13.390.525
1zzqH4BNitric oxide synthase, brain1.14.13.390.524
3ej8H4BNitric oxide synthase, inducible1.14.13.390.523
3rqmH4BNitric oxide synthase, brain1.14.13.390.523
4js9H4BNitric oxide synthase, inducible1.14.13.390.522
3b3nH4BNitric oxide synthase, brain1.14.13.390.521
3nlzH4BNitric oxide synthase, brain1.14.13.390.521
3rqkH4BNitric oxide synthase, brain1.14.13.390.521
3tymH4BNitric oxide synthase, brain1.14.13.390.521
1dwxH4BNitric oxide synthase, inducible1.14.13.390.520
1p6kH4BNitric oxide synthase, brain1.14.13.390.518
3e7iH4BNitric oxide synthase, inducible1.14.13.390.518
3pneH4BNitric oxide synthase, brain1.14.13.390.518
3jwuH4BNitric oxide synthase, brain1.14.13.390.517
3rqjH4BNitric oxide synthase, brain1.14.13.390.516
4fw0H4BNitric oxide synthase, brain1.14.13.390.516
4euxH4BNitric oxide synthase, brain1.14.13.390.515
4gqeH4BNitric oxide synthase, brain1.14.13.390.515
4fvzH4BNitric oxide synthase, brain1.14.13.390.514
4k5gH4BNitric oxide synthase, brain1.14.13.390.514
1zzuH4BNitric oxide synthase, brain1.14.13.390.513
3jwtH4BNitric oxide synthase, brain1.14.13.390.513
3n5yH4BNitric oxide synthase, brain1.14.13.390.513
3uftH4BNitric oxide synthase, brain1.14.13.390.512
4imwH4BNitric oxide synthase, brain1.14.13.390.512
4jsfH4BNitric oxide synthase, brain1.14.13.390.512
2y37A54Nitric oxide synthase, inducible1.14.13.390.511
4jsiH4BNitric oxide synthase, brain1.14.13.390.510
3nlyH4BNitric oxide synthase, brain1.14.13.390.509
3ufuH4BNitric oxide synthase, brain1.14.13.390.509
3dqrH4BNitric oxide synthase, brain1.14.13.390.508
3jwvH4BNitric oxide synthase, brain1.14.13.390.508
4luxH4BNitric oxide synthase, brain1.14.13.390.508
3nloH4BNitric oxide synthase, brain1.14.13.390.507
4cx5H4BNitric oxide synthase, brain1.14.13.390.507
1zzrH4BNitric oxide synthase, brain1.14.13.390.506
3nlkH4BNitric oxide synthase, brain1.14.13.390.506
1qw514WNitric oxide synthase, inducible1.14.13.390.505
5aglH4BNitric oxide synthase, brain1.14.13.390.505
2hx3H4BNitric oxide synthase, brain1.14.13.390.504
3rqlH4BNitric oxide synthase, brain1.14.13.390.504
3jx2H4BNitric oxide synthase, brain1.14.13.390.503
1m9jCLWNitric oxide synthase, endothelial1.14.13.390.502
4cx3H4BNitric oxide synthase, brain1.14.13.390.502
3n5vH4BNitric oxide synthase, brain1.14.13.390.501
3nnyH4BNitric oxide synthase, brain1.14.13.390.501
1rs7H4BNitric oxide synthase, brain1.14.13.390.500
4imtH4BNitric oxide synthase, brain1.14.13.390.500
3nlnH4BNitric oxide synthase, brain1.14.13.390.497
3ufoH4BNitric oxide synthase, brain1.14.13.390.495
4imuH4BNitric oxide synthase, brain1.14.13.390.491
4k5fH4BNitric oxide synthase, brain1.14.13.390.491
3nlpH4BNitric oxide synthase, brain1.14.13.390.490
3ufrH4BNitric oxide synthase, brain1.14.13.390.490
1m9m6NINitric oxide synthase, endothelial1.14.13.390.489
3n65XFJNitric oxide synthase, brain1.14.13.390.488
3nljH4BNitric oxide synthase, brain1.14.13.390.487
4fvxH4BNitric oxide synthase, brain1.14.13.390.486
4jshH4BNitric oxide synthase, brain1.14.13.390.486
3svqH4BNitric oxide synthase, brain1.14.13.390.484
3ufpH4BNitric oxide synthase, brain1.14.13.390.481
3ebf332Nitric oxide synthase, inducible1.14.13.390.480
1m8h6NINitric oxide synthase, inducible1.14.13.390.479
1m9tINENitric oxide synthase, inducible1.14.13.390.479
3n62XFJNitric oxide synthase, brain1.14.13.390.479
4cx4H4BNitric oxide synthase, brain1.14.13.390.479
3b3pJI7Nitric oxide synthase, brain1.14.13.390.478
3jx4H4BNitric oxide synthase, brain1.14.13.390.478
3ufsHW6Nitric oxide synthase, brain1.14.13.390.478
3nlv3XANitric oxide synthase, brain1.14.13.390.477
3ufvHW9Nitric oxide synthase, brain1.14.13.390.476
2g6iHBINitric oxide synthase, brain1.14.13.390.475
2g6j7APNitric oxide synthase, brain1.14.13.390.475
3jx5H4BNitric oxide synthase, brain1.14.13.390.475
3n5yXFLNitric oxide synthase, brain1.14.13.390.475
1mmvH4BNitric oxide synthase, brain1.14.13.390.474
3q9aH4BNitric oxide synthase, brain1.14.13.390.474
3svpH4BNitric oxide synthase, brain1.14.13.390.474
1m9k7NINitric oxide synthase, endothelial1.14.13.390.473
3ufwH4BNitric oxide synthase, brain1.14.13.390.473
3jt9H4BNitric oxide synthase, brain1.14.13.390.472
3jx3H4BNitric oxide synthase, brain1.14.13.390.472
3nlw3XFNitric oxide synthase, brain1.14.13.390.471
1r35I58Nitric oxide synthase, inducible1.14.13.390.470
3n66XFNNitric oxide synthase, brain1.14.13.390.470
2hx44HXNitric oxide synthase, brain1.14.13.390.469
1p6jDP9Nitric oxide synthase, brain1.14.13.390.468
3jx6H4BNitric oxide synthase, brain1.14.13.390.468
3nlrH4BNitric oxide synthase, brain1.14.13.390.468
3tym08RNitric oxide synthase, brain1.14.13.390.468
3jt3H4BNitric oxide synthase, brain1.14.13.390.467
3jt4H4BNitric oxide synthase, brain1.14.13.390.467
3n5xXFKNitric oxide synthase, brain1.14.13.390.467
3e7mAT2Nitric oxide synthase, inducible1.14.13.390.466
3pnf8BXNitric oxide synthase, brain1.14.13.390.466
3q99H4BNitric oxide synthase, brain1.14.13.390.466
3nlqH4BNitric oxide synthase, brain1.14.13.390.465
4jsfQJ4Nitric oxide synthase, brain1.14.13.390.465
1zzqDP9Nitric oxide synthase, brain1.14.13.390.464
3jtaH4BNitric oxide synthase, brain1.14.13.390.464
3n5wXFJNitric oxide synthase, brain1.14.13.390.464
3n5zXFMNitric oxide synthase, brain1.14.13.390.464
3tylAXWNitric oxide synthase, brain1.14.13.390.464
3e7iB2Nitric oxide synthase, inducible1.14.13.390.463
3nlz3XDNitric oxide synthase, brain1.14.13.390.463
3nnz59WNitric oxide synthase, brain1.14.13.390.463
4jseH4BNitric oxide synthase, brain1.14.13.390.463
3jt6H4BNitric oxide synthase, brain1.14.13.390.462
3png8CXNitric oxide synthase, brain1.14.13.390.462
4imt1EWNitric oxide synthase, brain1.14.13.390.462
3jt7H4BNitric oxide synthase, brain1.14.13.390.461
3jwtJI5Nitric oxide synthase, brain1.14.13.390.461
3ufqHW5Nitric oxide synthase, brain1.14.13.390.461
4d1oH4BNitric oxide synthase, endothelial1.14.13.390.461
4imw1EVNitric oxide synthase, brain1.14.13.390.461
3jwuJ11Nitric oxide synthase, brain1.14.13.390.460
3jt5H4BNitric oxide synthase, brain1.14.13.390.459
3nlkJSSNitric oxide synthase, brain1.14.13.390.459
3pne8AXNitric oxide synthase, brain1.14.13.390.459
1m9rINENitric oxide synthase, endothelial1.14.13.390.458
3fc5H4BNitric oxide synthase, brain1.14.13.390.458
3nloJSRNitric oxide synthase, brain1.14.13.390.458
3eah327Nitric oxide synthase, endothelial1.14.13.390.457
3n61H4BNitric oxide synthase, brain1.14.13.390.457
3rqjY2BNitric oxide synthase, brain1.14.13.390.457
4fvyH4BNitric oxide synthase, brain1.14.13.390.457
5agkH4BNitric oxide synthase, brain1.14.13.390.457
1rs6DP2Nitric oxide synthase, brain1.14.13.390.456
1zzuDP1Nitric oxide synthase, brain1.14.13.390.456
3jx2JI4Nitric oxide synthase, brain1.14.13.390.456
3rqkX2CNitric oxide synthase, brain1.14.13.390.456
1zvlH4BNitric oxide synthase, brain1.14.13.390.455
3n60XFNNitric oxide synthase, brain1.14.13.390.455
5agpH4BNitric oxide synthase, brain1.14.13.390.455
3eai328Nitric oxide synthase, inducible1.14.13.390.454
3ufoHW4Nitric oxide synthase, brain1.14.13.390.454
3ufwHW0Nitric oxide synthase, brain1.14.13.390.454
4jsgQ10Nitric oxide synthase, brain1.14.13.390.454
3jwsJI4Nitric oxide synthase, brain1.14.13.390.453
3jx0JI4Nitric oxide synthase, brain1.14.13.390.453
3nodH4BNitric oxide synthase, inducible1.14.13.390.453
3rqmX2ENitric oxide synthase, brain1.14.13.390.452
4k5e1Q7Nitric oxide synthase, brain1.14.13.390.451
3nlnJRSNitric oxide synthase, brain1.14.13.390.450
3ufuHW8Nitric oxide synthase, brain1.14.13.390.450
4cx3HW8Nitric oxide synthase, brain1.14.13.390.450
1vafARRNitric oxide synthase, inducible1.14.13.390.449
3nny59RNitric oxide synthase, brain1.14.13.390.449
3rqlX2DNitric oxide synthase, brain1.14.13.390.448
3uftHW7Nitric oxide synthase, brain1.14.13.390.448
4cx5HW8Nitric oxide synthase, brain1.14.13.390.448
4euxHW1Nitric oxide synthase, brain1.14.13.390.448
3jt8H4BNitric oxide synthase, brain1.14.13.390.447
4jsiQ05Nitric oxide synthase, brain1.14.13.390.447
3n5vXFHNitric oxide synthase, brain1.14.13.390.446
3nly3XCNitric oxide synthase, brain1.14.13.390.446
3ufrH5WNitric oxide synthase, brain1.14.13.390.443
4cx4HW9Nitric oxide synthase, brain1.14.13.390.443
4luxQJ8Nitric oxide synthase, brain1.14.13.390.443
3b3oJI3Nitric oxide synthase, brain1.14.13.390.442
3jx4J11Nitric oxide synthase, brain1.14.13.390.442
3svpJK5Nitric oxide synthase, brain1.14.13.390.442
3jx3JI5Nitric oxide synthase, brain1.14.13.390.441
4k5fQ14Nitric oxide synthase, brain1.14.13.390.440