sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1jkx	138	Phosphoribosylglycinamide formyltransferase

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
1jkx	138	Phosphoribosylglycinamide formyltransferase	/	1.000
1c2t	GAR	Phosphoribosylglycinamide formyltransferase	/	0.531
1c2t	NHS	Phosphoribosylglycinamide formyltransferase	/	0.512
1men	GAR	Trifunctional purine biosynthetic protein adenosine-3	2.1.2.2	0.506
1c3e	GAR	Phosphoribosylglycinamide formyltransferase	/	0.497
1cde	GAR	Phosphoribosylglycinamide formyltransferase	/	0.491
1cde	DZF	Phosphoribosylglycinamide formyltransferase	/	0.469
1c3e	NHR	Phosphoribosylglycinamide formyltransferase	/	0.464