sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1gia | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1gia | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 1.000 | |
| 1gil | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.663 | |
| 1azt | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.557 | |
| 3c16 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.523 | |
| 1got | GDP | Guanine nucleotide-binding protein G(t) subunit alpha-1 | / | 0.520 | |
| 4pao | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.516 | |
| 3c15 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.503 | |
| 1cul | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.501 | |
| 3ums | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.501 | |
| 3r7w | GNP | GTP-binding protein GTR2 | / | 0.477 | |
| 4pan | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.471 | |
| 5doz | NDP | JamJ | / | 0.470 | |
| 4c0b | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.468 | |
| 2fe4 | GDP | Ras-related protein Rab-6B | / | 0.465 | |
| 3w6u | NAP | 6-phosphogluconate dehydrogenase, NAD-binding protein | / | 0.463 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.463 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.462 | |
| 5ch7 | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.461 | |
| 4fid | GDP | G protein alpha subunit, putative | / | 0.458 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.457 | |
| 1y3a | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.456 | |
| 5bsf | NAD | Pyrroline-5-carboxylate reductase | / | 0.456 | |
| 2eu8 | AP5 | Adenylate kinase | / | 0.450 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.449 | |
| 3vhx | GTP | ADP-ribosylation factor 6 | / | 0.446 | |
| 5l3r | GCP | Cell division protein FtsY homolog, chloroplastic | / | 0.446 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.444 | |
| 3b1x | GNP | Ferrous iron transport protein B | / | 0.443 | |
| 3pcr | GTP | ADP-ribosylation factor 6 | / | 0.443 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.442 | |
| 2dgn | DOI | Adenylosuccinate synthetase isozyme 1 | / | 0.442 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.440 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.440 |