sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5k2a | ZMA | Adenosine receptor A2a |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 5k2a | ZMA | Adenosine receptor A2a | / | 1.000 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.828 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.688 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.654 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.653 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.651 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.632 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.599 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.591 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.572 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.561 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.552 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.511 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.498 | |
| 4ug2 | NGI | Adenosine receptor A2a | / | 0.495 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.475 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.465 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.461 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.458 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.457 | |
| 4equ | G6I | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.455 | |
| 4gi2 | NAP | Crotonyl-CoA carboxylase/reductase | / | 0.454 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.453 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.452 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.451 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.450 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.449 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.448 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.445 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.444 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.443 | |
| 2pmd | GNP | Translation initiation factor 2 subunit gamma | / | 0.442 | |
| 3nal | DBK | Calcium-transporting ATPase | / | 0.442 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.442 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.442 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.441 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.441 | |
| 2y98 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.440 |