sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5h8t | RTL | Retinol-binding protein 1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 5h8t | RTL | Retinol-binding protein 1 | / | 1.000 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.584 | |
| 5hbs | RTL | Retinol-binding protein 1 | / | 0.584 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.505 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.501 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.483 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.470 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.461 | |
| 3u8h | BHP | Phospholipase A2, membrane associated | / | 0.460 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.459 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.459 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.458 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.458 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.457 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.456 | |
| 1nhz | 486 | Glucocorticoid receptor | / | 0.455 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.455 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.455 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.453 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.453 | |
| 1psd | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.451 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.451 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.451 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.451 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.451 | |
| 1qkn | RAL | Estrogen receptor beta | / | 0.450 | |
| 2jla | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.450 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.450 | |
| 1uom | PTI | Estrogen receptor | / | 0.449 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.449 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.449 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.447 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.447 | |
| 3uwl | FOZ | Thymidylate synthase | / | 0.446 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.446 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.445 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.445 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.445 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.444 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.444 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.444 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.443 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.443 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 3up3 | XCA | aceDAF-12 | / | 0.442 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.442 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.442 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.442 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.442 | |
| 1fml | RTL | Retinol dehydratase | / | 0.441 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 3c0g | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.440 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.440 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.440 |