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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
5fklTDCTetracycline repressor protein class D

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
5fklTDCTetracycline repressor protein class D/1.000
4auxXTCTetracycline repressor protein class D/0.640
2xpuTDCTetracycline repressor protein class D/0.630
2trtTACTetracycline repressor protein class D/0.622
2xpwOTCTetracycline repressor protein class D/0.622
5fkmTDCTetracycline repressor protein class D/0.622
4b3aTACTetracycline repressor protein class D/0.600
2o7oDXTTetracycline repressor protein class D/0.592
2xpvMIYTetracycline repressor protein class D/0.583
1orkATCTetracycline repressor protein class D/0.565
2vkeTACTetracycline repressor protein class D/0.559
5fkoTDCTetracycline repressor protein class D/0.550
4abzT1CTetracycline repressor protein class D/0.542
2xb5I7TTetracycline repressor protein class D/0.536
4b1rITCTetracycline repressor protein class D/0.511
5fknTDCTetracycline repressor protein class D/0.511
2tctCTCTetracycline repressor protein class D/0.506
4v2gITCTetracycline repressor protein class D/0.495
2fj1CTCTetracycline repressor protein class D/0.494
4d7mTDCTetracycline repressor protein class D/0.490
2x9dITCTetracycline repressor protein class D/0.482
2vkvTDCTetracycline repressor protein class D/0.479
2vprTDCTetracycline repressor protein class H/0.474
2xrlDXTTetracycline repressor protein class D/0.466