scPDB - Distribution of Binding site Similarity values of 5fe1 entry / Site 2

Distribution of Binding site similarity measured by Shaper

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Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
5fe1	12Q	Histone acetyltransferase KAT2B	2.3.1.48

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
5fe1	12Q	Histone acetyltransferase KAT2B	2.3.1.48	1.000
3dhc	CYK	N-acyl homoserine lactonase AiiA	3.1.1.81	0.484
4nqn	Y1Z	Bromodomain-containing protein 9	/	0.478
1odc	A8B	Acetylcholinesterase	3.1.1.7	0.477
1zgb	A1E	Acetylcholinesterase	3.1.1.7	0.473
2pk3	A2R	GDP-6-deoxy-D-mannose reductase	/	0.469
3sqx	ANP	ATP-dependent RNA helicase MSS116, mitochondrial	3.6.4.13	0.469
2whq	HI6	Acetylcholinesterase	3.1.1.7	0.464
4bfx	ZVX	Pantothenate kinase	2.7.1.33	0.460
3mau	EXT	Putative sphingosine-1-phosphate lyase	/	0.458
2c94	TSF	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.456
3qto	10P	Prothrombin	3.4.21.5	0.455
1c4u	IH1	Prothrombin	3.4.21.5	0.454
1nzq	162	Prothrombin	3.4.21.5	0.453
2hxz	H7J	Cathepsin S	3.4.22.27	0.453
2xys	SY9	Soluble acetylcholine receptor	/	0.453
3dy8	5GP	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.453
4bf9	FMN	tRNA-dihydrouridine(16) synthase	/	0.450
4dym	IYZ	Activin receptor type-1	2.7.11.30	0.450
2gjl	FMN	Nitronate monooxygenase	1.13.12.16	0.449
2o1s	TDP	1-deoxy-D-xylulose-5-phosphate synthase	2.2.1.7	0.448
3c1k	T15	Prothrombin	3.4.21.5	0.448
4ask	K0I	Lysine-specific demethylase 6B	1.14.11	0.448
1mu6	CDA	Prothrombin	3.4.21.5	0.447
2ekl	NAD	D-3-phosphoglycerate dehydrogenase	/	0.447
2rd6	78P	Poly [ADP-ribose] polymerase 1	2.4.2.30	0.447
4jhz	1KV	Beta-glucuronidase	3.2.1.31	0.447
1lce	TMF	Thymidylate synthase	/	0.446
2zfq	45U	Prothrombin	3.4.21.5	0.446
4az2	9MU	Prothrombin	3.4.21.5	0.446
1z71	L17	Prothrombin	3.4.21.5	0.445
2cek	N8T	Acetylcholinesterase	3.1.1.7	0.445
2zfr	46U	Prothrombin	3.4.21.5	0.445
4g2j	0WF	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.445
2bf4	FAD	NADPH--cytochrome P450 reductase	/	0.444
3ivx	FG6	Pantothenate synthetase	6.3.2.1	0.444
3jus	BCD	Lanosterol 14-alpha demethylase	1.14.13.70	0.444
3lpg	Z78	Beta-glucuronidase	3.2.1.31	0.444
3tne	RIT	Candidapepsin-1	3.4.23.24	0.444
4hfp	15U	Prothrombin	3.4.21.5	0.444
5cmx	0G6	Prothrombin	3.4.21.5	0.444
7kme	ACE_0BN_CHG_PRR	Prothrombin	3.4.21.5	0.444
1nm6	L86	Prothrombin	3.4.21.5	0.443
3mjr	AC2	Deoxycytidine kinase	2.7.1.74	0.443
5dw6	0T1	Succinyl-CoA:acetate CoA-transferase	/	0.442
2x6o	2TC	Tetracycline repressor protein class D	/	0.441
3mpi	FAD	Glutaryl-CoA dehydrogenase	1.3.99.32	0.441
1c3x	8IG	Purine nucleoside phosphorylase	2.4.2.1	0.440
1efa	NPF	Lactose operon repressor	/	0.440
2ab8	MTP	Adenosine kinase	2.7.1.20	0.440
2bf4	FMN	NADPH--cytochrome P450 reductase	/	0.440
2i4p	DRH	Peroxisome proliferator-activated receptor gamma	/	0.440
3drc	MTX	Dihydrofolate reductase	1.5.1.3	0.440
3hyg	099	A disintegrin and metalloproteinase with thrombospondin motifs 5	3.4.24	0.440
4jlm	1NN	Deoxycytidine kinase	2.7.1.74	0.440
4s1i	PLP	Pyridoxal kinase, putative	/	0.440
4z63	ILE_THR_GLN_TYS_TYS	Phytosulfokine receptor 1	2.7.11.1	0.440
5kwv	ANP	Pantothenate synthetase	/	0.440