sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5erm | 210 | Fusicoccadiene synthase | 4.2.3.43 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 5erm | 210 | Fusicoccadiene synthase | 4.2.3.43 | 1.000 | |
| 4ea2 | RWZ | Dehydrosqualene synthase | / | 0.463 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 3lg5 | BTM | Epi-isozizaene synthase | 4.2.3.37 | 0.456 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.455 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.454 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.451 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2aou | CQA | Histamine N-methyltransferase | 2.1.1.8 | 0.449 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2gg2 | U12 | Methionine aminopeptidase | / | 0.448 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.447 | |
| 4o6f | SAH | N-lysine methyltransferase SMYD2 | / | 0.447 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.446 | |
| 1h69 | ARH | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 2q94 | A04 | Methionine aminopeptidase | / | 0.445 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.445 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2vqb | NAP | Putative flavin-containing monooxygenase | / | 0.444 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.442 | |
| 2re8 | GSU | Glutamine--tRNA ligase | 6.1.1.18 | 0.442 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.441 | |
| 3nhp | HGZ | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.440 |