sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5dib | NAD | Betaine-aldehyde dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 5dib | NAD | Betaine-aldehyde dehydrogenase | / | 1.000 | |
| 5ez4 | NAD | Betaine-aldehyde dehydrogenase | / | 0.608 | |
| 1o01 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.547 | |
| 1cw3 | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.533 | |
| 1a4z | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.483 | |
| 2qs1 | UB1 | Glutamate receptor ionotropic, kainate 1 | / | 0.476 | |
| 3rhr | NDP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 0.476 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.475 | |
| 3rhq | NAP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 0.462 | |
| 4gnz | NAP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 0.461 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.460 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.459 | |
| 4i8p | NAD | Aminoaldehyde dehydrogenase 1 | / | 0.457 | |
| 1wnb | NAI | Gamma-aminobutyraldehyde dehydrogenase | 1.2.1.19 | 0.456 | |
| 1dnp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.452 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.452 | |
| 1kqo | DND | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.451 | |
| 1dfo | FFO | Serine hydroxymethyltransferase | 2.1.2.1 | 0.449 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.449 | |
| 2zsd | COA | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 1tez | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.448 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.445 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 1zdf | UPG | Glycogenin-1 | 2.4.1.186 | 0.443 | |
| 2j07 | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.441 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 3arv | SAU | Chitinase A | / | 0.441 | |
| 3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 4yaw | 2AM | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.440 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 3ql6 | NIM | Lactoperoxidase | 1.11.1.7 | 0.440 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.440 |