scPDB - Distribution of Binding site Similarity values of 5cns entry / Site 3

Distribution of Binding site similarity measured by Shaper

You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
5cns	DAT	Ribonucleoside-diphosphate reductase 1 subunit alpha	1.17.4.1

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
5cns	DAT	Ribonucleoside-diphosphate reductase 1 subunit alpha	1.17.4.1	1.000
1udc	UFM	UDP-glucose 4-epimerase	5.1.3.2	0.460
3r1r	ATP	Ribonucleoside-diphosphate reductase 1 subunit alpha	1.17.4.1	0.458
1l7e	NAI	NAD(P) transhydrogenase subunit alpha part 1	1.6.1.2	0.446
1lrj	UD1	UDP-glucose 4-epimerase	5.1.3.2	0.442
1udb	UFG	UDP-glucose 4-epimerase	5.1.3.2	0.441
4lrl	TTP	HD domain protein	/	0.441
2fsv	NAD	NAD(P) transhydrogenase subunit alpha part 1	1.6.1.2	0.440
3keu	ATP	Pyridoxal kinase	2.7.1.35	0.440