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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
5c2tFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
5c2tFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/1.000
5c3jFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.634
4ytnFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.614
4kx6FADFumarate reductase flavoprotein subunit1.3.5.40.589
1kf6FADFumarate reductase flavoprotein subunit1.3.5.40.560
3sfeFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.554
1qo8FADFumarate reductase flavoprotein subunit/0.536
1d4dFADFumarate reductase flavoprotein subunit1.3.5.40.520
1knrFADL-aspartate oxidase1.4.3.160.517
1d4cFADFumarate reductase flavoprotein subunit1.3.5.40.470
2du8FADD-amino-acid oxidase1.4.3.30.467
2rgoFADAlpha-Glycerophosphate Oxidase/0.458
3ctyFADProbable thioredoxin reductase/0.457
3vqrFADPutative oxidoreductase/0.451
3sglFADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC/0.449
2gh5FADGlutathione reductase, mitochondrial1.8.1.70.448
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.447
1f0xFADD-lactate dehydrogenase1.1.1.280.446
2fjbSFDAdenylylsulfate reductase, subunit A (AprA)/0.446
3bg7FADPyranose 2-oxidase/0.446
3s5wFADL-ornithine N(5)-monooxygenase/0.440