sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5azg | ASP_PHE_THR_PHE_LEU | Protein lgg-1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 5azg | ASP_PHE_THR_PHE_LEU | Protein lgg-1 | / | 1.000 | |
| 2pup | ADP | Methylthioribose kinase | 2.7.1.100 | 0.460 | |
| 4c77 | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.459 | |
| 5ab6 | CAA | Nonspecific lipid-transfer protein, putative | / | 0.459 | |
| 3wdl | ATP | 4-phosphopantoate--beta-alanine ligase | 6.3.2.36 | 0.458 | |
| 5ab7 | MLC | Nonspecific lipid-transfer protein, putative | / | 0.457 | |
| 1tll | NAP | Nitric oxide synthase, brain | 1.14.13.39 | 0.456 | |
| 3p23 | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.456 | |
| 3w2w | ATP | CRISPR system Cmr subunit Cmr2 | / | 0.456 | |
| 4eaj | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.456 | |
| 1pvo | ANP | Transcription termination factor Rho | 3.6.4 | 0.454 | |
| 2o2q | NAP | Cytosolic 10-formyltetrahydrofolate dehydrogenase | 1.5.1.6 | 0.454 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.452 | |
| 4a0s | CO8 | Octenoyl-CoA reductase/carboxylase | / | 0.448 | |
| 3af4 | GCP | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 4to6 | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.447 | |
| 3lu6 | IMX | Serum albumin | / | 0.445 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.443 | |
| 3tdk | UPG | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.442 | |
| 3up5 | NAP | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.442 | |
| 1mh1 | GNP | Ras-related C3 botulinum toxin substrate 1 | / | 0.441 | |
| 4df4 | 0L3 | DNA polymerase I, thermostable | 2.7.7.7 | 0.441 | |
| 2q0f | UTP | Poly(A) polymerase, putative | / | 0.440 |